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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCRS1
All Species:
22.73
Human Site:
S122
Identified Species:
41.67
UniProt:
Q96EZ8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EZ8
NP_001012300.1
462
51803
S122
L
T
K
R
V
K
K
S
K
Q
P
L
Q
V
T
Chimpanzee
Pan troglodytes
XP_509047
513
57528
S173
L
T
K
R
V
K
K
S
K
Q
P
L
Q
V
T
Rhesus Macaque
Macaca mulatta
XP_001109790
462
51406
S122
L
T
K
R
V
K
K
S
K
Q
P
L
Q
V
T
Dog
Lupus familis
XP_850537
462
51831
S122
L
T
K
R
V
K
K
S
K
Q
P
L
Q
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99L90
462
51674
S122
L
T
K
R
V
K
K
S
K
Q
P
L
Q
V
T
Rat
Rattus norvegicus
NP_001013124
462
51804
S122
L
T
K
R
V
K
K
S
K
Q
P
L
Q
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512056
254
28409
Chicken
Gallus gallus
XP_001232507
447
50517
L128
K
P
A
D
D
L
L
L
I
N
A
V
L
Q
T
Frog
Xenopus laevis
NP_001080873
453
50959
L123
P
L
Q
V
T
K
D
L
G
R
W
K
P
A
D
Zebra Danio
Brachydanio rerio
NP_998438
472
53117
K130
S
S
M
T
K
R
M
K
K
N
K
Q
P
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647852
578
63519
P167
L
S
V
D
S
L
L
P
G
T
P
S
T
V
A
Honey Bee
Apis mellifera
XP_624688
469
53205
K124
A
S
N
A
P
G
R
K
N
K
K
N
K
N
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797067
874
96141
Q438
P
P
P
P
P
P
P
Q
A
V
K
E
E
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90
94.1
99.1
N.A.
98.2
98.4
N.A.
45
85.2
82
75.4
N.A.
44.6
51.5
N.A.
33.9
Protein Similarity:
100
90
94.5
99.3
N.A.
98.4
98.6
N.A.
48
90.9
90
86.2
N.A.
59
69.5
N.A.
43.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
6.6
6.6
6.6
N.A.
20
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
13.3
20
26.6
N.A.
26.6
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
0
0
0
8
0
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
8
0
8
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
16
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
8
0
47
0
8
54
47
16
54
8
24
8
8
0
8
% K
% Leu:
54
8
0
0
0
16
16
16
0
0
0
47
8
8
0
% L
% Met:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
8
16
0
8
0
8
0
% N
% Pro:
16
16
8
8
16
8
8
8
0
0
54
0
16
0
0
% P
% Gln:
0
0
8
0
0
0
0
8
0
47
0
8
47
8
8
% Q
% Arg:
0
0
0
47
0
8
8
0
0
8
0
0
0
0
0
% R
% Ser:
8
24
0
0
8
0
0
47
0
0
0
8
0
0
0
% S
% Thr:
0
47
0
8
8
0
0
0
0
8
0
0
8
0
54
% T
% Val:
0
0
8
8
47
0
0
0
0
8
0
8
0
62
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _