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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF125
All Species:
12.73
Human Site:
S95
Identified Species:
35
UniProt:
Q96EQ8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EQ8
NP_060301.2
232
26454
S95
D
V
A
K
R
M
K
S
E
Y
K
N
C
A
E
Chimpanzee
Pan troglodytes
Q6J212
228
25690
F98
C
H
G
C
R
K
K
F
F
L
S
K
I
R
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547620
416
45697
S279
D
V
A
K
R
M
K
S
E
Y
Q
N
C
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9R0
233
26343
S96
D
I
A
K
R
M
K
S
E
Y
Q
N
C
A
E
Rat
Rattus norvegicus
Q6J2U6
229
25646
F99
C
H
G
C
R
K
D
F
V
L
S
K
I
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3B2
244
26625
S100
S
V
E
K
Q
L
S
S
Y
K
A
P
C
R
G
Frog
Xenopus laevis
Q3KPU8
241
26755
S97
N
V
D
K
Q
L
S
S
Y
K
A
P
C
R
G
Zebra Danio
Brachydanio rerio
Q6IWL4
542
61788
L129
N
F
A
K
R
E
I
L
S
L
T
V
K
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511080
475
53825
I162
D
N
Y
T
R
R
E
I
E
Q
L
K
R
D
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.1
N.A.
51.9
N.A.
85.8
31.8
N.A.
N.A.
32.7
32.3
20.1
N.A.
20
N.A.
N.A.
N.A.
Protein Similarity:
100
55.1
N.A.
53.8
N.A.
92.2
55.5
N.A.
N.A.
50
51.4
29.3
N.A.
31.3
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
N.A.
86.6
N.A.
86.6
6.6
N.A.
N.A.
26.6
26.6
20
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
N.A.
93.3
N.A.
100
6.6
N.A.
N.A.
40
46.6
26.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
45
0
0
0
0
0
0
0
23
0
0
23
12
% A
% Cys:
23
0
0
23
0
0
0
0
0
0
0
0
56
12
12
% C
% Asp:
45
0
12
0
0
0
12
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
12
0
0
12
12
0
45
0
0
0
0
0
34
% E
% Phe:
0
12
0
0
0
0
0
23
12
0
0
0
0
0
0
% F
% Gly:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
23
% G
% His:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
12
12
0
0
0
0
23
0
0
% I
% Lys:
0
0
0
67
0
23
45
0
0
23
12
34
12
0
0
% K
% Leu:
0
0
0
0
0
23
0
12
0
34
12
0
0
0
0
% L
% Met:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% M
% Asn:
23
12
0
0
0
0
0
0
0
0
0
34
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% P
% Gln:
0
0
0
0
23
0
0
0
0
12
23
0
0
0
0
% Q
% Arg:
0
0
0
0
78
12
0
0
0
0
0
0
12
45
0
% R
% Ser:
12
0
0
0
0
0
23
56
12
0
23
0
0
0
23
% S
% Thr:
0
0
0
12
0
0
0
0
0
0
12
0
0
12
0
% T
% Val:
0
45
0
0
0
0
0
0
12
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
0
23
34
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _