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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCOS All Species: 8.79
Human Site: S545 Identified Species: 14.87
UniProt: Q96EN8 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96EN8 NP_060417.2 888 98153 S545 G S R V W N N S S T V N A V P
Chimpanzee Pan troglodytes XP_512097 888 98083 S545 G S R V W N N S S T V N A V P
Rhesus Macaque Macaca mulatta XP_001105941 857 94684 S547 G S G V W N N S S T T V N A V
Dog Lupus familis XP_547604 858 94451 S524 G V C S D L P S T V G A A D L
Cat Felis silvestris
Mouse Mus musculus Q14CH1 862 94994 P534 S V C N G S Y P D T N I M D L
Rat Rattus norvegicus NP_001101895 698 76459 D402 V A G I L N G D L G S H I V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506730 921 102647 P554 R K D L P L D P E L W S G S A
Chicken Gallus gallus XP_419048 810 90102 Y514 T V T N I Y L Y P I K S C S A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VD33 831 92380 K530 V S E V T M S K D G K K D G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRA2 781 88085 L485 S Y L A T K P L Q R I Q F I E
Honey Bee Apis mellifera XP_394734 768 86407 L472 I K D V Q T L L V M I K E C F
Nematode Worm Caenorhab. elegans Q21657 709 79704 G413 G A I R I S F G R T S T E H D
Sea Urchin Strong. purpuratus XP_001202774 797 88490 R501 H S I T D A P R L S G I Y L Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5X8 819 91784 K523 P S E D L E S K E S F P S H Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 90.8 77.5 N.A. 73.9 60.1 N.A. 62.7 56.3 N.A. 49.8 N.A. 37.7 38.8 30 40.8
Protein Similarity: 100 99.3 93.1 84.1 N.A. 82.2 67.4 N.A. 74.2 69.3 N.A. 66.6 N.A. 56 58.5 48.8 57.7
P-Site Identity: 100 100 60 20 N.A. 6.6 13.3 N.A. 0 0 N.A. 13.3 N.A. 0 6.6 13.3 6.6
P-Site Similarity: 100 100 60 26.6 N.A. 13.3 33.3 N.A. 20 6.6 N.A. 20 N.A. 13.3 13.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. 35.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 54.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 8 0 8 0 0 0 0 0 8 22 8 15 % A
% Cys: 0 0 15 0 0 0 0 0 0 0 0 0 8 8 0 % C
% Asp: 0 0 15 8 15 0 8 8 15 0 0 0 8 15 8 % D
% Glu: 0 0 15 0 0 8 0 0 15 0 0 0 15 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 8 0 8 0 8 % F
% Gly: 36 0 15 0 8 0 8 8 0 15 15 0 8 8 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 8 0 15 0 % H
% Ile: 8 0 15 8 15 0 0 0 0 8 15 15 8 8 0 % I
% Lys: 0 15 0 0 0 8 0 15 0 0 15 15 0 0 0 % K
% Leu: 0 0 8 8 15 15 15 15 15 8 0 0 0 8 15 % L
% Met: 0 0 0 0 0 8 0 0 0 8 0 0 8 0 0 % M
% Asn: 0 0 0 15 0 29 22 0 0 0 8 15 8 0 0 % N
% Pro: 8 0 0 0 8 0 22 15 8 0 0 8 0 0 15 % P
% Gln: 0 0 0 0 8 0 0 0 8 0 0 8 0 0 0 % Q
% Arg: 8 0 15 8 0 0 0 8 8 8 0 0 0 0 0 % R
% Ser: 15 43 0 8 0 15 15 29 22 15 15 15 8 15 8 % S
% Thr: 8 0 8 8 15 8 0 0 8 36 8 8 0 0 8 % T
% Val: 15 22 0 36 0 0 0 0 8 8 15 8 0 22 8 % V
% Trp: 0 0 0 0 22 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 8 0 0 0 8 8 8 0 0 0 0 8 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _