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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOCOS
All Species:
19.09
Human Site:
S412
Identified Species:
32.31
UniProt:
Q96EN8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EN8
NP_060417.2
888
98153
S412
S
Q
V
D
K
M
A
S
L
Y
N
I
H
L
R
Chimpanzee
Pan troglodytes
XP_512097
888
98083
S412
S
Q
V
D
K
M
A
S
L
Y
N
I
H
L
R
Rhesus Macaque
Macaca mulatta
XP_001105941
857
94684
S414
S
Q
V
D
K
M
A
S
L
Y
N
I
H
L
R
Dog
Lupus familis
XP_547604
858
94451
F402
I
H
V
R
T
G
C
F
C
N
T
G
A
C
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q14CH1
862
94994
S412
S
Q
V
D
K
M
A
S
L
Y
N
I
H
L
R
Rat
Rattus norvegicus
NP_001101895
698
76459
F280
E
E
M
V
K
K
H
F
Q
A
G
H
V
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506730
921
102647
S429
S
Q
V
D
K
M
A
S
L
H
N
I
H
V
R
Chicken
Gallus gallus
XP_419048
810
90102
G392
L
I
D
G
R
P
T
G
S
V
R
I
S
F
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VD33
831
92380
Q404
G
R
T
V
G
Y
S
Q
V
D
K
M
A
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRA2
781
88085
L363
N
G
E
P
L
V
K
L
Y
N
K
V
G
Y
Q
Honey Bee
Apis mellifera
XP_394734
768
86407
L350
A
K
F
L
Y
T
S
L
L
M
L
H
H
N
N
Nematode Worm
Caenorhab. elegans
Q21657
709
79704
T291
I
S
S
I
R
N
L
T
H
H
L
C
K
N
A
Sea Urchin
Strong. purpuratus
XP_001202774
797
88490
I379
R
L
A
S
L
H
D
I
H
L
R
T
G
C
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5X8
819
91784
K401
P
T
V
T
F
N
L
K
R
P
D
G
S
W
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
90.8
77.5
N.A.
73.9
60.1
N.A.
62.7
56.3
N.A.
49.8
N.A.
37.7
38.8
30
40.8
Protein Similarity:
100
99.3
93.1
84.1
N.A.
82.2
67.4
N.A.
74.2
69.3
N.A.
66.6
N.A.
56
58.5
48.8
57.7
P-Site Identity:
100
100
100
6.6
N.A.
100
6.6
N.A.
86.6
6.6
N.A.
0
N.A.
0
13.3
0
0
P-Site Similarity:
100
100
100
13.3
N.A.
100
20
N.A.
100
13.3
N.A.
26.6
N.A.
26.6
33.3
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
36
0
0
8
0
0
15
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
8
0
0
8
0
22
0
% C
% Asp:
0
0
8
36
0
0
8
0
0
8
8
0
0
0
0
% D
% Glu:
8
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
8
0
0
15
0
0
0
0
0
8
15
% F
% Gly:
8
8
0
8
8
8
0
8
0
0
8
15
15
0
15
% G
% His:
0
8
0
0
0
8
8
0
15
15
0
15
43
0
0
% H
% Ile:
15
8
0
8
0
0
0
8
0
0
0
43
0
0
0
% I
% Lys:
0
8
0
0
43
8
8
8
0
0
15
0
8
0
0
% K
% Leu:
8
8
0
8
15
0
15
15
43
8
15
0
0
29
8
% L
% Met:
0
0
8
0
0
36
0
0
0
8
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
15
0
0
0
15
36
0
0
15
8
% N
% Pro:
8
0
0
8
0
8
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
36
0
0
0
0
0
8
8
0
0
0
0
0
15
% Q
% Arg:
8
8
0
8
15
0
0
0
8
0
15
0
0
0
36
% R
% Ser:
36
8
8
8
0
0
15
36
8
0
0
0
15
8
0
% S
% Thr:
0
8
8
8
8
8
8
8
0
0
8
8
0
0
0
% T
% Val:
0
0
50
15
0
8
0
0
8
8
0
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
8
8
0
0
8
29
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _