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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOCOS
All Species:
18.79
Human Site:
S251
Identified Species:
31.79
UniProt:
Q96EN8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EN8
NP_060417.2
888
98153
S251
S
T
S
P
L
D
L
S
A
H
Q
A
D
F
V
Chimpanzee
Pan troglodytes
XP_512097
888
98083
S251
S
T
S
P
L
D
L
S
A
H
Q
A
D
F
V
Rhesus Macaque
Macaca mulatta
XP_001105941
857
94684
S253
S
T
S
P
L
D
L
S
A
H
Q
A
D
F
V
Dog
Lupus familis
XP_547604
858
94451
L251
L
F
G
F
P
T
G
L
G
A
L
L
V
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q14CH1
862
94994
S251
S
T
S
P
L
D
L
S
A
H
Q
A
D
F
I
Rat
Rattus norvegicus
NP_001101895
698
76459
G129
R
K
G
Y
F
G
G
G
T
A
A
V
Y
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506730
921
102647
T268
S
T
S
P
L
D
L
T
S
H
P
A
D
F
I
Chicken
Gallus gallus
XP_419048
810
90102
A241
Y
F
P
K
K
S
I
A
E
R
F
E
D
G
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VD33
831
92380
Y251
S
P
L
D
L
S
Q
Y
P
A
D
F
V
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRA2
781
88085
H212
G
E
K
K
K
N
M
H
N
D
Y
Y
I
C
L
Honey Bee
Apis mellifera
XP_394734
768
86407
L199
A
Q
C
N
F
S
G
L
K
Y
P
L
T
W
I
Nematode Worm
Caenorhab. elegans
Q21657
709
79704
E140
V
N
E
E
S
I
L
E
H
E
I
P
D
V
E
Sea Urchin
Strong. purpuratus
XP_001202774
797
88490
M228
V
T
I
S
F
Y
K
M
F
G
F
P
T
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5X8
819
91784
C250
L
I
D
A
A
K
G
C
A
T
L
P
P
D
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
90.8
77.5
N.A.
73.9
60.1
N.A.
62.7
56.3
N.A.
49.8
N.A.
37.7
38.8
30
40.8
Protein Similarity:
100
99.3
93.1
84.1
N.A.
82.2
67.4
N.A.
74.2
69.3
N.A.
66.6
N.A.
56
58.5
48.8
57.7
P-Site Identity:
100
100
100
0
N.A.
93.3
0
N.A.
73.3
6.6
N.A.
13.3
N.A.
0
0
13.3
6.6
P-Site Similarity:
100
100
100
0
N.A.
100
0
N.A.
93.3
20
N.A.
20
N.A.
20
26.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
0
8
36
22
8
36
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
8
0
36
0
0
0
8
8
0
50
8
0
% D
% Glu:
0
8
8
8
0
0
0
8
8
8
0
8
0
0
8
% E
% Phe:
0
15
0
8
22
0
0
0
8
0
15
8
0
36
0
% F
% Gly:
8
0
15
0
0
8
29
8
8
8
0
0
0
15
0
% G
% His:
0
0
0
0
0
0
0
8
8
36
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
8
8
0
0
0
8
0
8
0
29
% I
% Lys:
0
8
8
15
15
8
8
0
8
0
0
0
0
0
0
% K
% Leu:
15
0
8
0
43
0
43
15
0
0
15
15
0
8
22
% L
% Met:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
8
0
0
8
0
0
0
0
8
8
% N
% Pro:
0
8
8
36
8
0
0
0
8
0
15
22
8
8
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
29
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
43
0
36
8
8
22
0
29
8
0
0
0
0
0
0
% S
% Thr:
0
43
0
0
0
8
0
8
8
8
0
0
15
0
8
% T
% Val:
15
0
0
0
0
0
0
0
0
0
0
8
15
8
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
8
0
0
8
0
8
0
8
0
8
8
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _