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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHF21B
All Species:
7.27
Human Site:
T252
Identified Species:
20
UniProt:
Q96EK2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EK2
NP_001129334.1
531
57455
T252
T
A
E
S
R
P
P
T
E
E
P
S
Q
G
A
Chimpanzee
Pan troglodytes
XP_001136599
405
43804
I151
I
K
V
Q
P
L
L
I
S
A
D
N
K
V
I
Rhesus Macaque
Macaca mulatta
XP_001112561
634
70234
G318
T
P
G
T
R
L
A
G
P
Q
T
V
Q
L
S
Dog
Lupus familis
XP_851453
601
63884
T320
T
G
E
L
R
P
P
T
E
E
P
S
Q
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8C966
487
52983
K228
K
E
D
Q
P
P
S
K
E
N
P
E
K
I
A
Rat
Rattus norvegicus
NP_001124152
494
53609
K228
K
E
D
Q
P
P
S
K
E
N
P
E
K
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507820
638
70589
T343
T
I
K
S
H
T
E
T
E
E
K
Q
T
E
S
Chicken
Gallus gallus
XP_425507
456
49886
I202
K
E
E
N
P
E
K
I
A
F
M
V
A
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693915
797
86009
S286
L
Q
I
S
N
L
N
S
D
L
K
T
V
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.2
33.5
52
N.A.
81.1
80.7
N.A.
35.2
64.2
N.A.
28.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
74
50.1
61.4
N.A.
85.6
85.5
N.A.
50.6
72.8
N.A.
40.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
20
86.6
N.A.
26.6
26.6
N.A.
33.3
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
40
86.6
N.A.
40
40
N.A.
46.6
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
12
0
12
12
0
0
12
0
45
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
23
0
0
0
0
0
12
0
12
0
0
0
0
% D
% Glu:
0
34
34
0
0
12
12
0
56
34
0
23
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
12
12
0
0
0
0
12
0
0
0
0
0
23
12
% G
% His:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
12
12
0
0
0
0
23
0
0
0
0
0
23
12
% I
% Lys:
34
12
12
0
0
0
12
23
0
0
23
0
34
12
0
% K
% Leu:
12
0
0
12
0
34
12
0
0
12
0
0
0
23
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
12
12
0
12
0
0
23
0
12
0
0
0
% N
% Pro:
0
12
0
0
45
45
23
0
12
0
45
0
0
0
12
% P
% Gln:
0
12
0
34
0
0
0
0
0
12
0
12
34
0
0
% Q
% Arg:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
34
0
0
23
12
12
0
0
23
0
0
23
% S
% Thr:
45
0
0
12
0
12
0
34
0
0
12
12
12
0
0
% T
% Val:
0
0
12
0
0
0
0
0
0
0
0
23
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _