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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEH1L
All Species:
10.61
Human Site:
S353
Identified Species:
21.21
UniProt:
Q96EE3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EE3
NP_001013455.1
360
39649
S353
L
Q
N
S
L
N
G
S
S
A
G
R
K
H
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_860726
360
39739
S353
L
Q
N
S
L
N
G
S
S
S
S
R
K
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2U0
360
39756
T353
L
Q
N
S
L
N
G
T
S
A
S
R
K
H
S
Rat
Rattus norvegicus
Q5XFW8
322
35529
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516945
324
35581
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4FZW5
360
39707
P353
Q
N
S
V
N
G
T
P
S
S
G
R
K
H
S
Zebra Danio
Brachydanio rerio
Q6TGU2
364
39798
T353
Q
M
I
V
G
A
A
T
A
G
R
K
K
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610343
354
39496
Honey Bee
Apis mellifera
XP_396810
408
45120
T353
S
S
T
T
R
A
I
T
I
A
T
V
T
A
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781224
444
49387
N353
R
N
T
S
S
S
A
N
Q
Q
Q
Q
Q
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53011
349
39104
Red Bread Mold
Neurospora crassa
Q7RZF5
304
33367
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
98
N.A.
96.1
29.7
N.A.
86.3
N.A.
90.8
81.8
N.A.
53
58.5
N.A.
57.4
Protein Similarity:
100
N.A.
N.A.
99.1
N.A.
98
48.3
N.A.
87.7
N.A.
95.5
89
N.A.
70.5
72.3
N.A.
66.6
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
86.6
0
N.A.
0
N.A.
40
6.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
93.3
0
N.A.
0
N.A.
53.3
26.6
N.A.
0
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.5
26.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
43.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
17
0
9
25
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
9
25
0
0
9
17
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% H
% Ile:
0
0
9
0
0
0
9
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
42
0
0
% K
% Leu:
25
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
25
0
9
25
0
9
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
17
25
0
0
0
0
0
0
9
9
9
9
9
0
9
% Q
% Arg:
9
0
0
0
9
0
0
0
0
0
9
34
0
0
0
% R
% Ser:
9
9
9
34
9
9
0
17
34
17
17
0
0
0
34
% S
% Thr:
0
0
17
9
0
0
9
25
0
0
9
0
9
0
0
% T
% Val:
0
0
0
17
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _