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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC99
All Species:
34.85
Human Site:
Y222
Identified Species:
63.89
UniProt:
Q96EA4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EA4
NP_060255.3
605
70120
Y222
R
E
K
E
A
V
S
Y
Y
N
A
L
E
K
A
Chimpanzee
Pan troglodytes
XP_001148181
602
69364
Y222
R
E
K
E
A
V
S
Y
Y
N
A
L
E
K
A
Rhesus Macaque
Macaca mulatta
XP_001091769
601
69887
Y222
R
E
K
E
A
V
S
Y
Y
N
A
L
E
K
A
Dog
Lupus familis
XP_536434
603
69824
Y222
R
E
K
E
A
V
S
Y
Y
N
A
L
E
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q923A2
608
70218
Y222
R
E
R
E
A
V
S
Y
Y
N
A
L
E
K
A
Rat
Rattus norvegicus
Q3KR99
597
69094
Y222
R
E
K
E
A
V
S
Y
Y
N
A
L
E
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508244
599
69687
Y222
R
E
K
E
V
V
S
Y
C
N
A
L
E
K
A
Chicken
Gallus gallus
XP_414505
608
71149
Y222
R
E
K
E
V
V
S
Y
C
N
A
L
E
K
A
Frog
Xenopus laevis
Q6NRW2
610
70759
Y223
R
E
K
E
A
V
G
Y
F
S
A
L
E
K
A
Zebra Danio
Brachydanio rerio
A7MD70
590
68945
C224
R
E
K
E
A
V
S
C
Y
N
A
L
E
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P10567
882
101931
L272
A
E
R
E
R
S
Q
L
Q
S
Q
L
H
Q
V
Sea Urchin
Strong. purpuratus
XP_794989
564
64872
K225
D
K
R
Q
A
I
E
K
K
M
I
S
L
Q
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LME2
871
99988
F307
L
D
K
K
N
L
T
F
K
E
K
F
D
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
91.4
87.5
N.A.
73.8
73.2
N.A.
66.1
59.5
54.4
46.1
N.A.
N.A.
N.A.
21
25.9
Protein Similarity:
100
96.8
94.7
93.5
N.A.
82.5
82.8
N.A.
80
75.6
71.9
64.6
N.A.
N.A.
N.A.
42.1
47.4
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
86.6
86.6
80
93.3
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
86.6
93.3
93.3
N.A.
N.A.
N.A.
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
70
0
0
0
0
0
77
0
0
0
77
% A
% Cys:
0
0
0
0
0
0
0
8
16
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
85
0
85
0
0
8
0
0
8
0
0
77
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% I
% Lys:
0
8
77
8
0
0
0
8
16
0
8
0
0
85
0
% K
% Leu:
8
0
0
0
0
8
0
8
0
0
0
85
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
70
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
8
0
8
0
8
0
0
16
0
% Q
% Arg:
77
0
24
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
70
0
0
16
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
16
77
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
54
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _