KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC99
All Species:
23.94
Human Site:
S576
Identified Species:
43.89
UniProt:
Q96EA4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EA4
NP_060255.3
605
70120
S576
K
E
G
K
E
T
S
S
K
L
E
K
E
T
C
Chimpanzee
Pan troglodytes
XP_001148181
602
69364
S573
K
E
G
K
E
T
A
S
K
L
E
K
E
T
C
Rhesus Macaque
Macaca mulatta
XP_001091769
601
69887
S572
K
E
G
K
E
T
A
S
K
L
E
K
E
T
C
Dog
Lupus familis
XP_536434
603
69824
S574
K
E
G
K
E
T
A
S
K
L
E
K
E
T
C
Cat
Felis silvestris
Mouse
Mus musculus
Q923A2
608
70218
S579
K
E
R
I
E
T
T
S
K
L
G
K
G
A
C
Rat
Rattus norvegicus
Q3KR99
597
69094
S568
K
E
R
K
E
A
T
S
K
L
E
K
G
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508244
599
69687
S570
K
E
E
E
E
T
T
S
K
P
E
R
K
A
R
Chicken
Gallus gallus
XP_414505
608
71149
I579
E
D
K
K
E
N
V
I
T
T
K
K
K
T
Q
Frog
Xenopus laevis
Q6NRW2
610
70759
R582
V
D
E
E
Q
E
K
R
K
Q
E
R
K
S
R
Zebra Danio
Brachydanio rerio
A7MD70
590
68945
W562
S
S
E
E
E
E
N
W
R
T
E
K
K
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P10567
882
101931
V648
R
A
R
K
Q
A
E
V
D
L
E
E
A
N
G
Sea Urchin
Strong. purpuratus
XP_794989
564
64872
S535
M
K
E
D
G
D
G
S
S
R
G
K
R
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LME2
871
99988
V702
E
E
R
Q
R
A
L
V
Q
L
Q
W
K
V
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
91.4
87.5
N.A.
73.8
73.2
N.A.
66.1
59.5
54.4
46.1
N.A.
N.A.
N.A.
21
25.9
Protein Similarity:
100
96.8
94.7
93.5
N.A.
82.5
82.8
N.A.
80
75.6
71.9
64.6
N.A.
N.A.
N.A.
42.1
47.4
P-Site Identity:
100
93.3
93.3
93.3
N.A.
60
60
N.A.
46.6
26.6
13.3
20
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
100
100
100
100
N.A.
66.6
66.6
N.A.
73.3
53.3
53.3
46.6
N.A.
N.A.
N.A.
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
24
24
0
0
0
0
0
8
24
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
39
% C
% Asp:
0
16
0
8
0
8
0
0
8
0
0
0
0
0
0
% D
% Glu:
16
62
31
24
70
16
8
0
0
0
70
8
31
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
31
0
8
0
8
0
0
0
16
0
16
8
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
54
8
8
54
0
0
8
0
62
0
8
70
39
0
8
% K
% Leu:
0
0
0
0
0
0
8
0
0
62
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
8
16
0
0
0
8
8
8
0
0
0
8
% Q
% Arg:
8
0
31
0
8
0
0
8
8
8
0
16
8
8
16
% R
% Ser:
8
8
0
0
0
0
8
62
8
0
0
0
0
8
8
% S
% Thr:
0
0
0
0
0
47
24
0
8
16
0
0
0
39
0
% T
% Val:
8
0
0
0
0
0
8
16
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _