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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC99 All Species: 20
Human Site: S355 Identified Species: 36.67
UniProt: Q96EA4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96EA4 NP_060255.3 605 70120 S355 D S M E S K P S V D S G T L E
Chimpanzee Pan troglodytes XP_001148181 602 69364 S352 D S M E S K P S V D S G T L E
Rhesus Macaque Macaca mulatta XP_001091769 601 69887 S355 E S M E S K P S V D S G A L E
Dog Lupus familis XP_536434 603 69824 S355 E S T E S K L S A N S G T L E
Cat Felis silvestris
Mouse Mus musculus Q923A2 608 70218 S355 E S M E S R P S T S D T A C V
Rat Rattus norvegicus Q3KR99 597 69094 S357 M E S K S S T S D S A C A L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508244 599 69687 S358 E S K P S G S S S N P V P L E
Chicken Gallus gallus XP_414505 608 71149 A355 E N M E E C R A S T S S K G G
Frog Xenopus laevis Q6NRW2 610 70759 S356 E N G P V A S S C D G L G Q G
Zebra Danio Brachydanio rerio A7MD70 590 68945 P357 K D H H P H P P S N E G E L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P10567 882 101931 G397 E Q L E R Q V G E L K V R I D
Sea Urchin Strong. purpuratus XP_794989 564 64872 R322 M D L D G L K R F Y Q S K L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LME2 871 99988 E473 E L E T L Q K E S E S H Q L Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.5 91.4 87.5 N.A. 73.8 73.2 N.A. 66.1 59.5 54.4 46.1 N.A. N.A. N.A. 21 25.9
Protein Similarity: 100 96.8 94.7 93.5 N.A. 82.5 82.8 N.A. 80 75.6 71.9 64.6 N.A. N.A. N.A. 42.1 47.4
P-Site Identity: 100 100 86.6 66.6 N.A. 40 26.6 N.A. 33.3 20 13.3 20 N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: 100 100 93.3 80 N.A. 53.3 40 N.A. 46.6 40 26.6 33.3 N.A. N.A. N.A. 40 26.6
Percent
Protein Identity: N.A. N.A. N.A. 20.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 41.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 8 8 0 8 0 24 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 8 0 0 8 0 8 0 % C
% Asp: 16 16 0 8 0 0 0 0 8 31 8 0 0 0 8 % D
% Glu: 62 8 8 54 8 0 0 8 8 8 8 0 8 0 54 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 8 8 0 8 0 0 8 39 8 8 16 % G
% His: 0 0 8 8 0 8 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 8 0 8 8 0 31 16 0 0 0 8 0 16 0 8 % K
% Leu: 0 8 16 0 8 8 8 0 0 8 0 8 0 70 0 % L
% Met: 16 0 39 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 16 0 0 0 0 0 0 0 24 0 0 0 0 0 % N
% Pro: 0 0 0 16 8 0 39 8 0 0 8 0 8 0 0 % P
% Gln: 0 8 0 0 0 16 0 0 0 0 8 0 8 8 8 % Q
% Arg: 0 0 0 0 8 8 8 8 0 0 0 0 8 0 0 % R
% Ser: 0 47 8 0 54 8 16 62 31 16 47 16 0 0 0 % S
% Thr: 0 0 8 8 0 0 8 0 8 8 0 8 24 0 0 % T
% Val: 0 0 0 0 8 0 8 0 24 0 0 16 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _