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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4C
All Species:
13.64
Human Site:
Y426
Identified Species:
21.43
UniProt:
Q96DT6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DT6
NP_116241.2
458
52497
Y426
V
N
G
H
S
R
D
Y
D
F
T
S
T
T
T
Chimpanzee
Pan troglodytes
XP_001159697
366
41520
G335
K
Q
S
Y
Y
F
A
G
F
Q
D
D
S
L
I
Rhesus Macaque
Macaca mulatta
XP_001086218
458
52551
Y426
V
N
G
H
S
R
D
Y
D
F
T
S
T
T
T
Dog
Lupus familis
XP_852273
458
52523
Y426
V
N
G
H
S
R
D
Y
D
F
T
S
T
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q811C2
458
52068
F426
V
N
G
H
S
K
D
F
D
F
T
S
T
A
A
Rat
Rattus norvegicus
NP_001101418
458
52091
F426
V
N
G
H
S
R
D
F
D
F
T
S
T
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
Y426
V
K
G
H
S
R
D
Y
D
F
A
S
G
P
T
Chicken
Gallus gallus
Q6PZ02
393
44512
P362
Q
P
S
H
F
S
N
P
D
V
L
N
L
T
P
Frog
Xenopus laevis
Q5XH30
450
51749
F417
V
N
G
H
A
Q
D
F
D
F
V
C
T
P
V
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
A363
Q
P
S
H
L
I
T
A
D
V
L
N
L
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
T591
A
A
G
S
H
H
T
T
P
Q
S
S
H
Q
T
Honey Bee
Apis mellifera
XP_393739
477
54008
D439
F
C
E
G
S
G
K
D
L
H
Q
K
I
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
G681
I
V
R
D
G
R
C
G
D
W
Q
N
K
N
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
A426
C
L
R
A
L
K
L
A
E
E
S
N
G
A
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
D475
I
I
S
V
S
P
Y
D
P
A
R
G
Q
G
G
Conservation
Percent
Protein Identity:
100
79.9
98.2
94.5
N.A.
90.3
89.5
N.A.
83.2
28.1
68.1
26.8
N.A.
26.5
30.3
N.A.
28
Protein Similarity:
100
79.9
98.9
97.3
N.A.
95.6
95.4
N.A.
88
42.5
82.7
46
N.A.
42
46.3
N.A.
41.4
P-Site Identity:
100
0
100
100
N.A.
73.3
80
N.A.
73.3
20
53.3
20
N.A.
20
6.6
N.A.
20
P-Site Similarity:
100
13.3
100
100
N.A.
86.6
86.6
N.A.
73.3
33.3
73.3
26.6
N.A.
26.6
6.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
7
0
7
14
0
7
7
0
0
20
14
% A
% Cys:
7
7
0
0
0
0
7
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
7
0
0
47
14
67
0
7
7
0
0
0
% D
% Glu:
0
0
7
0
0
0
0
0
7
7
0
0
0
7
0
% E
% Phe:
7
0
0
0
7
7
0
20
7
47
0
0
0
0
0
% F
% Gly:
0
0
54
7
7
7
0
14
0
0
0
7
14
7
7
% G
% His:
0
0
0
60
7
7
0
0
0
7
0
0
7
0
0
% H
% Ile:
14
7
0
0
0
7
0
0
0
0
0
0
7
0
14
% I
% Lys:
7
7
0
0
0
14
7
0
0
0
0
7
7
0
0
% K
% Leu:
0
7
0
0
14
0
7
0
7
0
14
0
14
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
40
0
0
0
0
7
0
0
0
0
27
0
7
0
% N
% Pro:
0
14
0
0
0
7
0
7
14
0
0
0
0
14
20
% P
% Gln:
14
7
0
0
0
7
0
0
0
14
14
0
7
7
0
% Q
% Arg:
0
0
14
0
0
40
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
27
7
54
7
0
0
0
0
14
47
7
0
0
% S
% Thr:
0
0
0
0
0
0
14
7
0
0
34
0
40
34
40
% T
% Val:
47
7
0
7
0
0
0
0
0
14
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
0
7
27
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _