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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATG4C All Species: 36.06
Human Site: Y387 Identified Species: 56.67
UniProt: Q96DT6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96DT6 NP_116241.2 458 52497 Y387 P S C T I G F Y C R N V Q D F
Chimpanzee Pan troglodytes XP_001159697 366 41520 R296 V I I L V P V R L G G E R T N
Rhesus Macaque Macaca mulatta XP_001086218 458 52551 Y387 P S C T I G F Y C R N V Q D F
Dog Lupus familis XP_852273 458 52523 Y387 P S C T I G F Y C R N V Q D F
Cat Felis silvestris
Mouse Mus musculus Q811C2 458 52068 Y387 P S C T I G F Y C R N V Q D F
Rat Rattus norvegicus NP_001101418 458 52091 Y387 P S C T I G F Y C R N V Q D F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514370 459 52127 Y387 P S C T V G F Y C R N V Q D F
Chicken Gallus gallus Q6PZ02 393 44512 C323 S I A V G F F C H T E E D F N
Frog Xenopus laevis Q5XH30 450 51749 Y378 P S C T V G F Y C R N A R E F
Zebra Danio Brachydanio rerio Q6DG88 394 44435 F324 P S I A A G F F C Q T E D D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650452 668 74736 Y552 P S C C I G F Y C A T K S D F
Honey Bee Apis mellifera XP_393739 477 54008 Y400 P S C C V G F Y F H N K M Q F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786847 723 81931 Y642 P S C T I G F Y I R T E E Q F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8S929 467 51510 H387 D V D T S S Y H C N V L R Y V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S3X7 506 55337 D436 L R Q L H I G D M D P S M L I
Conservation
Percent
Protein Identity: 100 79.9 98.2 94.5 N.A. 90.3 89.5 N.A. 83.2 28.1 68.1 26.8 N.A. 26.5 30.3 N.A. 28
Protein Similarity: 100 79.9 98.9 97.3 N.A. 95.6 95.4 N.A. 88 42.5 82.7 46 N.A. 42 46.3 N.A. 41.4
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 93.3 6.6 73.3 46.6 N.A. 66.6 53.3 N.A. 66.6
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 100 6.6 93.3 60 N.A. 66.6 60 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. 22.7 N.A. 21.5
Protein Similarity: N.A. N.A. N.A. 41.1 N.A. 39.3
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. 0
P-Site Similarity: N.A. N.A. N.A. 40 N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 7 0 0 0 0 7 0 7 0 0 0 % A
% Cys: 0 0 67 14 0 0 0 7 67 0 0 0 0 0 0 % C
% Asp: 7 0 7 0 0 0 0 7 0 7 0 0 14 54 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 7 27 7 7 0 % E
% Phe: 0 0 0 0 0 7 80 7 7 0 0 0 0 7 74 % F
% Gly: 0 0 0 0 7 74 7 0 0 7 7 0 0 0 0 % G
% His: 0 0 0 0 7 0 0 7 7 7 0 0 0 0 0 % H
% Ile: 0 14 14 0 47 7 0 0 7 0 0 0 0 0 7 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 % K
% Leu: 7 0 0 14 0 0 0 0 7 0 0 7 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 14 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 54 0 0 0 14 % N
% Pro: 74 0 0 0 0 7 0 0 0 0 7 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 7 0 0 40 14 0 % Q
% Arg: 0 7 0 0 0 0 0 7 0 54 0 0 20 0 0 % R
% Ser: 7 74 0 0 7 7 0 0 0 0 0 7 7 0 0 % S
% Thr: 0 0 0 60 0 0 0 0 0 7 20 0 0 7 0 % T
% Val: 7 7 0 7 27 0 7 0 0 0 7 40 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 67 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _