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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4C
All Species:
34.55
Human Site:
Y306
Identified Species:
54.29
UniProt:
Q96DT6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DT6
NP_116241.2
458
52497
Y306
G
E
R
T
N
T
D
Y
L
E
F
V
K
G
I
Chimpanzee
Pan troglodytes
XP_001159697
366
41520
H215
P
L
A
L
F
G
L
H
Q
L
I
E
Y
G
K
Rhesus Macaque
Macaca mulatta
XP_001086218
458
52551
Y306
G
E
R
T
N
T
D
Y
L
E
F
V
K
G
I
Dog
Lupus familis
XP_852273
458
52523
Y306
G
E
R
T
N
T
D
Y
L
D
F
V
K
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q811C2
458
52068
Y306
G
E
R
T
N
T
D
Y
L
E
F
V
K
G
V
Rat
Rattus norvegicus
NP_001101418
458
52091
Y306
G
E
R
T
N
I
D
Y
L
E
F
V
K
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
Y306
G
E
R
T
N
I
D
Y
L
E
F
V
K
G
I
Chicken
Gallus gallus
Q6PZ02
393
44512
T242
I
N
E
A
Y
I
E
T
L
K
H
C
F
M
M
Frog
Xenopus laevis
Q5XH30
450
51749
Y297
G
E
R
T
N
M
E
Y
F
E
Y
V
K
G
I
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
E243
D
I
N
E
A
Y
I
E
P
L
K
Q
C
F
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
Y471
S
D
K
L
N
P
V
Y
A
H
C
L
K
L
L
Honey Bee
Apis mellifera
XP_393739
477
54008
Y319
A
D
K
L
N
P
V
Y
T
S
C
L
T
H
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
Y561
G
D
E
V
N
P
V
Y
I
R
P
I
Q
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
T306
S
K
G
Q
S
E
W
T
P
I
I
L
L
V
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
K355
C
T
R
L
G
I
D
K
I
N
Q
V
Y
E
E
Conservation
Percent
Protein Identity:
100
79.9
98.2
94.5
N.A.
90.3
89.5
N.A.
83.2
28.1
68.1
26.8
N.A.
26.5
30.3
N.A.
28
Protein Similarity:
100
79.9
98.9
97.3
N.A.
95.6
95.4
N.A.
88
42.5
82.7
46
N.A.
42
46.3
N.A.
41.4
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
86.6
N.A.
93.3
6.6
73.3
0
N.A.
20
13.3
N.A.
20
P-Site Similarity:
100
13.3
100
100
N.A.
100
93.3
N.A.
93.3
26.6
86.6
6.6
N.A.
46.6
40
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
7
0
0
0
7
0
0
0
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
14
7
7
0
0
% C
% Asp:
7
20
0
0
0
0
47
0
0
7
0
0
0
0
0
% D
% Glu:
0
47
14
7
0
7
14
7
0
40
0
7
0
7
7
% E
% Phe:
0
0
0
0
7
0
0
0
7
0
40
0
7
7
0
% F
% Gly:
54
0
7
0
7
7
0
0
0
0
0
0
0
54
0
% G
% His:
0
0
0
0
0
0
0
7
0
7
7
0
0
7
0
% H
% Ile:
7
7
0
0
0
27
7
0
14
7
14
7
0
0
34
% I
% Lys:
0
7
14
0
0
0
0
7
0
7
7
0
54
0
7
% K
% Leu:
0
7
0
27
0
0
7
0
47
14
0
20
7
7
20
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
14
% M
% Asn:
0
7
7
0
67
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
20
0
0
14
0
7
0
0
0
7
% P
% Gln:
0
0
0
7
0
0
0
0
7
0
7
7
7
0
0
% Q
% Arg:
0
0
54
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
14
0
0
0
7
0
0
0
0
7
0
0
0
7
0
% S
% Thr:
0
7
0
47
0
27
0
14
7
0
0
0
7
0
0
% T
% Val:
0
0
0
7
0
0
20
0
0
0
0
54
0
7
14
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
7
0
67
0
0
7
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _