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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4C
All Species:
16.67
Human Site:
Y220
Identified Species:
26.19
UniProt:
Q96DT6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DT6
NP_116241.2
458
52497
Y220
G
L
H
Q
L
I
E
Y
G
K
K
S
G
K
K
Chimpanzee
Pan troglodytes
XP_001159697
366
41520
D145
A
L
N
I
E
N
S
D
S
E
S
W
T
S
H
Rhesus Macaque
Macaca mulatta
XP_001086218
458
52551
Y220
G
L
H
Q
L
I
E
Y
G
K
K
S
G
K
K
Dog
Lupus familis
XP_852273
458
52523
Y220
G
L
H
Q
L
I
K
Y
G
K
K
S
G
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q811C2
458
52068
F220
G
L
H
R
L
I
E
F
G
K
K
S
G
K
K
Rat
Rattus norvegicus
NP_001101418
458
52091
F220
G
L
H
R
L
I
E
F
G
K
K
S
G
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
Y220
G
L
H
Q
L
T
E
Y
G
K
K
S
G
K
T
Chicken
Gallus gallus
Q6PZ02
393
44512
T172
V
H
I
A
M
D
N
T
V
V
M
E
E
I
R
Frog
Xenopus laevis
Q5XH30
450
51749
G221
V
K
L
G
K
N
S
G
K
V
A
G
D
W
Y
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
T173
V
H
V
A
M
D
N
T
V
V
I
E
E
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
P283
M
T
Y
R
R
E
F
P
I
M
N
G
S
N
Y
Honey Bee
Apis mellifera
XP_393739
477
54008
L235
S
I
H
T
L
V
S
L
G
A
L
W
G
K
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
I475
S
V
H
R
L
V
G
I
G
Q
N
N
G
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
A226
S
I
H
N
L
I
I
A
G
A
S
Y
G
L
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
Y280
S
L
H
N
F
V
K
Y
G
A
T
A
C
G
K
Conservation
Percent
Protein Identity:
100
79.9
98.2
94.5
N.A.
90.3
89.5
N.A.
83.2
28.1
68.1
26.8
N.A.
26.5
30.3
N.A.
28
Protein Similarity:
100
79.9
98.9
97.3
N.A.
95.6
95.4
N.A.
88
42.5
82.7
46
N.A.
42
46.3
N.A.
41.4
P-Site Identity:
100
6.6
100
93.3
N.A.
86.6
86.6
N.A.
86.6
0
0
6.6
N.A.
0
33.3
N.A.
40
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
86.6
13.3
0
13.3
N.A.
13.3
53.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
14
0
0
0
7
0
20
7
7
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
0
0
0
14
0
7
0
0
0
0
7
0
0
% D
% Glu:
0
0
0
0
7
7
34
0
0
7
0
14
14
0
0
% E
% Phe:
0
0
0
0
7
0
7
14
0
0
0
0
0
0
0
% F
% Gly:
40
0
0
7
0
0
7
7
67
0
0
14
60
7
0
% G
% His:
0
14
67
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
14
7
7
0
40
7
7
7
0
7
0
0
14
0
% I
% Lys:
0
7
0
0
7
0
14
0
7
40
40
0
0
54
54
% K
% Leu:
0
54
7
0
60
0
0
7
0
0
7
0
0
7
0
% L
% Met:
7
0
0
0
14
0
0
0
0
7
7
0
0
0
0
% M
% Asn:
0
0
7
14
0
14
14
0
0
0
14
7
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
27
0
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
27
7
0
0
0
0
0
0
0
0
0
14
% R
% Ser:
27
0
0
0
0
0
20
0
7
0
14
40
7
7
0
% S
% Thr:
0
7
0
7
0
7
0
14
0
0
7
0
7
0
7
% T
% Val:
20
7
7
0
0
20
0
0
14
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
14
0
7
0
% W
% Tyr:
0
0
7
0
0
0
0
34
0
0
0
7
0
0
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _