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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4C
All Species:
17.27
Human Site:
Y196
Identified Species:
27.14
UniProt:
Q96DT6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DT6
NP_116241.2
458
52497
Y196
H
E
M
R
N
E
V
Y
H
R
K
I
I
S
W
Chimpanzee
Pan troglodytes
XP_001159697
366
41520
A121
R
T
G
Q
M
L
L
A
Q
G
L
I
L
H
F
Rhesus Macaque
Macaca mulatta
XP_001086218
458
52551
Y196
H
E
M
R
N
E
I
Y
H
R
K
I
I
S
W
Dog
Lupus familis
XP_852273
458
52523
Y196
H
E
M
R
N
E
I
Y
H
R
K
I
I
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q811C2
458
52068
Y196
H
T
V
R
N
E
A
Y
H
R
K
I
I
S
W
Rat
Rattus norvegicus
NP_001101418
458
52091
Y196
H
A
V
Q
S
E
I
Y
H
R
Q
I
I
S
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
F196
D
E
M
R
N
E
G
F
H
R
K
I
I
S
W
Chicken
Gallus gallus
Q6PZ02
393
44512
A148
W
Y
G
P
N
T
V
A
Q
V
L
K
K
L
A
Frog
Xenopus laevis
Q5XH30
450
51749
I197
E
D
L
H
R
K
I
I
S
W
F
A
D
Y
P
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
A149
W
Y
G
P
N
T
V
A
Q
V
L
K
K
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
W259
N
Q
V
G
E
Q
P
W
E
E
G
I
E
G
F
Honey Bee
Apis mellifera
XP_393739
477
54008
R211
K
L
D
E
Y
N
H
R
L
I
I
K
S
F
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
R451
Q
E
M
L
Q
F
H
R
Q
I
V
R
W
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
E202
K
S
E
L
P
E
Q
E
Y
L
E
T
L
E
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
A256
R
R
G
T
D
L
D
A
E
K
D
I
I
A
L
Conservation
Percent
Protein Identity:
100
79.9
98.2
94.5
N.A.
90.3
89.5
N.A.
83.2
28.1
68.1
26.8
N.A.
26.5
30.3
N.A.
28
Protein Similarity:
100
79.9
98.9
97.3
N.A.
95.6
95.4
N.A.
88
42.5
82.7
46
N.A.
42
46.3
N.A.
41.4
P-Site Identity:
100
6.6
93.3
93.3
N.A.
80
60
N.A.
80
13.3
0
13.3
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
33.3
100
100
N.A.
86.6
93.3
N.A.
86.6
13.3
26.6
13.3
N.A.
46.6
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
7
27
0
0
0
7
0
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
7
0
7
0
7
0
0
0
7
0
7
0
0
% D
% Glu:
7
34
7
7
7
47
0
7
14
7
7
0
7
7
0
% E
% Phe:
0
0
0
0
0
7
0
7
0
0
7
0
0
14
14
% F
% Gly:
0
0
27
7
0
0
7
0
0
7
7
0
0
7
14
% G
% His:
34
0
0
7
0
0
14
0
40
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
0
0
27
7
0
14
7
60
47
0
0
% I
% Lys:
14
0
0
0
0
7
0
0
0
7
34
20
14
0
0
% K
% Leu:
0
7
7
14
0
14
7
0
7
7
20
0
14
14
7
% L
% Met:
0
0
34
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
47
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
14
7
0
7
0
0
0
0
0
0
0
14
% P
% Gln:
7
7
0
14
7
7
7
0
27
0
7
0
0
0
0
% Q
% Arg:
14
7
0
34
7
0
0
14
0
40
0
7
0
0
0
% R
% Ser:
0
7
0
0
7
0
0
0
7
0
0
0
7
40
0
% S
% Thr:
0
14
0
7
0
14
0
0
0
0
0
7
0
0
0
% T
% Val:
0
0
20
0
0
0
20
0
0
14
7
0
0
0
0
% V
% Trp:
14
0
0
0
0
0
0
7
0
7
0
0
7
0
40
% W
% Tyr:
0
14
0
0
7
0
0
34
7
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _