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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATG4C All Species: 11.21
Human Site: T58 Identified Species: 17.62
UniProt: Q96DT6 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96DT6 NP_116241.2 458 52497 T58 K Y E D E D K T L P A E S G C
Chimpanzee Pan troglodytes XP_001159697 366 41520
Rhesus Macaque Macaca mulatta XP_001086218 458 52551 T58 K Y E D E D K T L P A E S G C
Dog Lupus familis XP_852273 458 52523 L58 K F E D E N K L L P A R S G C
Cat Felis silvestris
Mouse Mus musculus Q811C2 458 52068 M58 K Y E D E S K M L P A R S G C
Rat Rattus norvegicus NP_001101418 458 52091 V58 K Y E D E S K V L P A R S G C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514370 459 52127 I58 K S E E D D G I P V R S N W A
Chicken Gallus gallus Q6PZ02 393 44512 F18 L R F E Y E D F P E T K E P V
Frog Xenopus laevis Q5XH30 450 51749 T58 K Y E D S G V T A D D C S N S
Zebra Danio Brachydanio rerio Q6DG88 394 44435 F19 R F G E I E D F P E T S D P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650452 668 74736 K99 A T A T P Q R K I S T S S R F
Honey Bee Apis mellifera XP_393739 477 54008 T61 E V D S K V K T K L L S M W N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786847 723 81931 T177 Q S S D R E R T K T A W T K F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8S929 467 51510 T71 G H K Q V C T T R N G W T A F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S3X7 506 55337 W66 R T I N E P V W C L G C S Y T
Conservation
Percent
Protein Identity: 100 79.9 98.2 94.5 N.A. 90.3 89.5 N.A. 83.2 28.1 68.1 26.8 N.A. 26.5 30.3 N.A. 28
Protein Similarity: 100 79.9 98.9 97.3 N.A. 95.6 95.4 N.A. 88 42.5 82.7 46 N.A. 42 46.3 N.A. 41.4
P-Site Identity: 100 0 100 73.3 N.A. 80 80 N.A. 20 0 40 0 N.A. 6.6 13.3 N.A. 20
P-Site Similarity: 100 0 100 86.6 N.A. 80 80 N.A. 40 20 40 26.6 N.A. 20 33.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 22.7 N.A. 21.5
Protein Similarity: N.A. N.A. N.A. 41.1 N.A. 39.3
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 0 0 0 0 7 0 40 0 0 7 7 % A
% Cys: 0 0 0 0 0 7 0 0 7 0 0 14 0 0 34 % C
% Asp: 0 0 7 47 7 20 14 0 0 7 7 0 7 0 0 % D
% Glu: 7 0 47 20 40 20 0 0 0 14 0 14 7 0 0 % E
% Phe: 0 14 7 0 0 0 0 14 0 0 0 0 0 0 20 % F
% Gly: 7 0 7 0 0 7 7 0 0 0 14 0 0 34 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 7 0 0 7 7 0 0 0 0 0 0 % I
% Lys: 47 0 7 0 7 0 40 7 14 0 0 7 0 7 0 % K
% Leu: 7 0 0 0 0 0 0 7 34 14 7 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 7 0 0 % M
% Asn: 0 0 0 7 0 7 0 0 0 7 0 0 7 7 7 % N
% Pro: 0 0 0 0 7 7 0 0 20 34 0 0 0 14 0 % P
% Gln: 7 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % Q
% Arg: 14 7 0 0 7 0 14 0 7 0 7 20 0 7 0 % R
% Ser: 0 14 7 7 7 14 0 0 0 7 0 27 54 0 7 % S
% Thr: 0 14 0 7 0 0 7 40 0 7 20 0 14 0 7 % T
% Val: 0 7 0 0 7 7 14 7 0 7 0 0 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 14 0 14 0 % W
% Tyr: 0 34 0 0 7 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _