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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4C
All Species:
11.21
Human Site:
T58
Identified Species:
17.62
UniProt:
Q96DT6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DT6
NP_116241.2
458
52497
T58
K
Y
E
D
E
D
K
T
L
P
A
E
S
G
C
Chimpanzee
Pan troglodytes
XP_001159697
366
41520
Rhesus Macaque
Macaca mulatta
XP_001086218
458
52551
T58
K
Y
E
D
E
D
K
T
L
P
A
E
S
G
C
Dog
Lupus familis
XP_852273
458
52523
L58
K
F
E
D
E
N
K
L
L
P
A
R
S
G
C
Cat
Felis silvestris
Mouse
Mus musculus
Q811C2
458
52068
M58
K
Y
E
D
E
S
K
M
L
P
A
R
S
G
C
Rat
Rattus norvegicus
NP_001101418
458
52091
V58
K
Y
E
D
E
S
K
V
L
P
A
R
S
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
I58
K
S
E
E
D
D
G
I
P
V
R
S
N
W
A
Chicken
Gallus gallus
Q6PZ02
393
44512
F18
L
R
F
E
Y
E
D
F
P
E
T
K
E
P
V
Frog
Xenopus laevis
Q5XH30
450
51749
T58
K
Y
E
D
S
G
V
T
A
D
D
C
S
N
S
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
F19
R
F
G
E
I
E
D
F
P
E
T
S
D
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
K99
A
T
A
T
P
Q
R
K
I
S
T
S
S
R
F
Honey Bee
Apis mellifera
XP_393739
477
54008
T61
E
V
D
S
K
V
K
T
K
L
L
S
M
W
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
T177
Q
S
S
D
R
E
R
T
K
T
A
W
T
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
T71
G
H
K
Q
V
C
T
T
R
N
G
W
T
A
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
W66
R
T
I
N
E
P
V
W
C
L
G
C
S
Y
T
Conservation
Percent
Protein Identity:
100
79.9
98.2
94.5
N.A.
90.3
89.5
N.A.
83.2
28.1
68.1
26.8
N.A.
26.5
30.3
N.A.
28
Protein Similarity:
100
79.9
98.9
97.3
N.A.
95.6
95.4
N.A.
88
42.5
82.7
46
N.A.
42
46.3
N.A.
41.4
P-Site Identity:
100
0
100
73.3
N.A.
80
80
N.A.
20
0
40
0
N.A.
6.6
13.3
N.A.
20
P-Site Similarity:
100
0
100
86.6
N.A.
80
80
N.A.
40
20
40
26.6
N.A.
20
33.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
0
0
7
0
40
0
0
7
7
% A
% Cys:
0
0
0
0
0
7
0
0
7
0
0
14
0
0
34
% C
% Asp:
0
0
7
47
7
20
14
0
0
7
7
0
7
0
0
% D
% Glu:
7
0
47
20
40
20
0
0
0
14
0
14
7
0
0
% E
% Phe:
0
14
7
0
0
0
0
14
0
0
0
0
0
0
20
% F
% Gly:
7
0
7
0
0
7
7
0
0
0
14
0
0
34
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
7
0
0
7
7
0
0
0
0
0
0
% I
% Lys:
47
0
7
0
7
0
40
7
14
0
0
7
0
7
0
% K
% Leu:
7
0
0
0
0
0
0
7
34
14
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
7
0
7
0
0
0
7
0
0
7
7
7
% N
% Pro:
0
0
0
0
7
7
0
0
20
34
0
0
0
14
0
% P
% Gln:
7
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
14
7
0
0
7
0
14
0
7
0
7
20
0
7
0
% R
% Ser:
0
14
7
7
7
14
0
0
0
7
0
27
54
0
7
% S
% Thr:
0
14
0
7
0
0
7
40
0
7
20
0
14
0
7
% T
% Val:
0
7
0
0
7
7
14
7
0
7
0
0
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
14
0
14
0
% W
% Tyr:
0
34
0
0
7
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _