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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4C
All Species:
26.67
Human Site:
T417
Identified Species:
41.9
UniProt:
Q96DT6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DT6
NP_116241.2
458
52497
T417
K
E
K
Y
P
L
F
T
F
V
N
G
H
S
R
Chimpanzee
Pan troglodytes
XP_001159697
366
41520
K326
C
V
G
I
I
G
G
K
P
K
Q
S
Y
Y
F
Rhesus Macaque
Macaca mulatta
XP_001086218
458
52551
T417
K
E
K
Y
P
L
F
T
F
V
N
G
H
S
R
Dog
Lupus familis
XP_852273
458
52523
T417
K
E
K
Y
P
L
F
T
F
V
N
G
H
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q811C2
458
52068
T417
K
E
K
Y
P
L
F
T
F
V
N
G
H
S
K
Rat
Rattus norvegicus
NP_001101418
458
52091
T417
K
E
K
Y
P
L
F
T
F
V
N
G
H
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
T417
K
E
K
Y
P
L
F
T
F
V
K
G
H
S
R
Chicken
Gallus gallus
Q6PZ02
393
44512
E353
L
P
M
F
E
L
V
E
R
Q
P
S
H
F
S
Frog
Xenopus laevis
Q5XH30
450
51749
T408
K
Q
N
Y
P
L
F
T
F
V
N
G
H
A
Q
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
D354
L
P
M
F
E
L
V
D
S
Q
P
S
H
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
D582
C
A
S
G
A
T
V
D
K
A
A
G
S
H
H
Honey Bee
Apis mellifera
XP_393739
477
54008
F430
E
K
I
D
Y
P
M
F
L
F
C
E
G
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
M672
S
H
S
S
D
Y
P
M
F
I
V
R
D
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
D417
R
D
K
D
D
F
D
D
F
C
L
R
A
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
K466
S
V
K
H
V
Q
G
K
S
I
I
S
V
S
P
Conservation
Percent
Protein Identity:
100
79.9
98.2
94.5
N.A.
90.3
89.5
N.A.
83.2
28.1
68.1
26.8
N.A.
26.5
30.3
N.A.
28
Protein Similarity:
100
79.9
98.9
97.3
N.A.
95.6
95.4
N.A.
88
42.5
82.7
46
N.A.
42
46.3
N.A.
41.4
P-Site Identity:
100
0
100
100
N.A.
93.3
100
N.A.
93.3
13.3
73.3
13.3
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
93.3
20
93.3
20
N.A.
6.6
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
0
0
0
0
7
7
0
7
7
0
% A
% Cys:
14
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% C
% Asp:
0
7
0
14
14
0
7
20
0
0
0
0
7
0
0
% D
% Glu:
7
40
0
0
14
0
0
7
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
14
0
7
47
7
60
7
0
0
0
7
7
% F
% Gly:
0
0
7
7
0
7
14
0
0
0
0
54
7
7
7
% G
% His:
0
7
0
7
0
0
0
0
0
0
0
0
60
7
7
% H
% Ile:
0
0
7
7
7
0
0
0
0
14
7
0
0
0
7
% I
% Lys:
47
7
54
0
0
0
0
14
7
7
7
0
0
0
14
% K
% Leu:
14
0
0
0
0
60
0
0
7
0
7
0
0
14
0
% L
% Met:
0
0
14
0
0
0
7
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
40
0
0
0
0
% N
% Pro:
0
14
0
0
47
7
7
0
7
0
14
0
0
0
7
% P
% Gln:
0
7
0
0
0
7
0
0
0
14
7
0
0
0
7
% Q
% Arg:
7
0
0
0
0
0
0
0
7
0
0
14
0
0
40
% R
% Ser:
14
0
14
7
0
0
0
0
14
0
0
27
7
54
7
% S
% Thr:
0
0
0
0
0
7
0
47
0
0
0
0
0
0
0
% T
% Val:
0
14
0
0
7
0
20
0
0
47
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
47
7
7
0
0
0
0
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _