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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4C
All Species:
17.58
Human Site:
T173
Identified Species:
27.62
UniProt:
Q96DT6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DT6
NP_116241.2
458
52497
T173
S
G
E
R
E
F
K
T
P
T
I
S
L
K
E
Chimpanzee
Pan troglodytes
XP_001159697
366
41520
I98
Y
R
E
E
F
P
Q
I
E
G
S
A
L
T
T
Rhesus Macaque
Macaca mulatta
XP_001086218
458
52551
T173
S
G
E
R
E
L
K
T
S
K
I
S
L
K
E
Dog
Lupus familis
XP_852273
458
52523
T173
S
G
E
S
E
L
K
T
P
T
V
S
Q
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q811C2
458
52068
T173
S
G
D
R
E
L
R
T
P
A
V
S
L
K
E
Rat
Rattus norvegicus
NP_001101418
458
52091
T173
S
G
E
R
E
L
R
T
P
A
V
S
L
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
P173
V
G
E
R
D
P
R
P
P
S
A
S
R
N
A
Chicken
Gallus gallus
Q6PZ02
393
44512
H125
K
D
S
Y
Y
S
I
H
Q
I
A
Q
M
G
V
Frog
Xenopus laevis
Q5XH30
450
51749
S174
P
E
N
E
E
Y
V
S
L
G
K
Q
P
L
Q
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
H126
K
D
S
Y
Y
S
I
H
Q
I
A
Q
M
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
I236
P
A
L
N
P
Q
Q
I
D
E
I
V
V
P
Q
Honey Bee
Apis mellifera
XP_393739
477
54008
R188
L
V
C
H
F
L
G
R
E
W
R
W
Q
P
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
I428
M
M
L
A
H
S
L
I
L
H
F
L
G
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
F179
I
R
S
S
Q
M
L
F
A
Q
A
L
L
F
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
S233
C
M
I
R
S
G
Q
S
L
L
A
N
A
I
L
Conservation
Percent
Protein Identity:
100
79.9
98.2
94.5
N.A.
90.3
89.5
N.A.
83.2
28.1
68.1
26.8
N.A.
26.5
30.3
N.A.
28
Protein Similarity:
100
79.9
98.9
97.3
N.A.
95.6
95.4
N.A.
88
42.5
82.7
46
N.A.
42
46.3
N.A.
41.4
P-Site Identity:
100
13.3
80
73.3
N.A.
66.6
73.3
N.A.
33.3
0
6.6
0
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
26.6
80
80
N.A.
86.6
86.6
N.A.
53.3
6.6
26.6
6.6
N.A.
26.6
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
0
7
14
34
7
7
0
7
% A
% Cys:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
7
0
7
0
0
0
7
0
0
0
0
0
7
% D
% Glu:
0
7
40
14
40
0
0
0
14
7
0
0
0
0
40
% E
% Phe:
0
0
0
0
14
7
0
7
0
0
7
0
0
7
0
% F
% Gly:
0
40
0
0
0
7
7
0
0
14
0
0
7
14
0
% G
% His:
0
0
0
7
7
0
0
14
0
7
0
0
0
0
7
% H
% Ile:
7
0
7
0
0
0
14
20
0
14
20
0
0
7
0
% I
% Lys:
14
0
0
0
0
0
20
0
0
7
7
0
0
34
0
% K
% Leu:
7
0
14
0
0
34
14
0
20
7
0
14
40
7
7
% L
% Met:
7
14
0
0
0
7
0
0
0
0
0
0
14
0
0
% M
% Asn:
0
0
7
7
0
0
0
0
0
0
0
7
0
7
0
% N
% Pro:
14
0
0
0
7
14
0
7
34
0
0
0
7
14
0
% P
% Gln:
0
0
0
0
7
7
20
0
14
7
0
20
14
0
14
% Q
% Arg:
0
14
0
40
0
0
20
7
0
0
7
0
7
7
0
% R
% Ser:
34
0
20
14
7
20
0
14
7
7
7
40
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
34
0
14
0
0
0
7
7
% T
% Val:
7
7
0
0
0
0
7
0
0
0
20
7
7
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% W
% Tyr:
7
0
0
14
14
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _