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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4C
All Species:
16.67
Human Site:
S451
Identified Species:
26.19
UniProt:
Q96DT6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DT6
NP_116241.2
458
52497
S451
K
K
Q
L
K
R
F
S
T
E
E
F
V
L
L
Chimpanzee
Pan troglodytes
XP_001159697
366
41520
Rhesus Macaque
Macaca mulatta
XP_001086218
458
52551
S451
K
K
R
L
K
R
F
S
M
E
E
F
V
L
L
Dog
Lupus familis
XP_852273
458
52523
S451
K
K
R
L
K
R
F
S
T
E
E
F
V
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q811C2
458
52068
S451
R
K
N
F
K
R
F
S
T
E
E
F
V
L
L
Rat
Rattus norvegicus
NP_001101418
458
52091
S451
K
K
N
F
K
R
F
S
T
E
E
F
V
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
F451
E
K
K
R
L
K
R
F
S
T
E
E
F
V
L
Chicken
Gallus gallus
Q6PZ02
393
44512
Frog
Xenopus laevis
Q5XH30
450
51749
F442
E
K
K
R
L
K
R
F
S
T
E
E
F
V
L
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
M616
S
F
S
R
G
R
C
M
D
H
E
R
D
E
M
Honey Bee
Apis mellifera
XP_393739
477
54008
D464
F
T
G
N
G
T
Y
D
D
D
L
D
E
C
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
G706
V
R
H
V
D
E
N
G
R
L
I
A
P
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
F451
I
N
Q
S
N
Y
G
F
A
D
D
D
S
E
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
Conservation
Percent
Protein Identity:
100
79.9
98.2
94.5
N.A.
90.3
89.5
N.A.
83.2
28.1
68.1
26.8
N.A.
26.5
30.3
N.A.
28
Protein Similarity:
100
79.9
98.9
97.3
N.A.
95.6
95.4
N.A.
88
42.5
82.7
46
N.A.
42
46.3
N.A.
41.4
P-Site Identity:
100
0
86.6
93.3
N.A.
80
86.6
N.A.
20
0
20
0
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
0
93.3
100
N.A.
86.6
86.6
N.A.
53.3
0
53.3
0
N.A.
20
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
0
0
7
0
0
7
14
14
7
14
7
0
7
% D
% Glu:
14
0
0
0
0
7
0
0
0
34
54
14
7
14
7
% E
% Phe:
7
7
0
14
0
0
34
20
0
0
0
34
14
0
0
% F
% Gly:
0
0
7
0
14
0
7
7
0
0
0
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
27
47
14
0
34
14
0
0
0
0
0
0
0
0
7
% K
% Leu:
0
0
0
20
14
0
0
0
0
7
7
0
0
34
47
% L
% Met:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
7
% M
% Asn:
0
7
14
7
7
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
7
14
20
0
40
14
0
7
0
0
7
0
0
0
% R
% Ser:
7
0
7
7
0
0
0
34
14
0
0
0
7
0
0
% S
% Thr:
0
7
0
0
0
7
0
0
27
14
0
0
0
0
0
% T
% Val:
7
0
0
7
0
0
0
0
0
0
0
0
34
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _