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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4C
All Species:
15.45
Human Site:
S440
Identified Species:
24.29
UniProt:
Q96DT6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DT6
NP_116241.2
458
52497
S440
T
N
E
E
D
L
F
S
E
D
E
K
K
Q
L
Chimpanzee
Pan troglodytes
XP_001159697
366
41520
C349
I
Y
M
D
P
H
Y
C
Q
S
F
V
D
V
S
Rhesus Macaque
Macaca mulatta
XP_001086218
458
52551
S440
T
N
E
E
D
L
F
S
E
D
E
K
K
R
L
Dog
Lupus familis
XP_852273
458
52523
S440
T
N
E
E
D
L
F
S
E
D
E
K
K
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q811C2
458
52068
S440
A
S
E
E
D
L
F
S
E
D
E
R
K
N
F
Rat
Rattus norvegicus
NP_001101418
458
52091
L440
A
S
E
E
D
L
F
L
E
D
E
K
K
N
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
F440
T
R
E
E
P
D
L
F
S
E
D
E
K
K
R
Chicken
Gallus gallus
Q6PZ02
393
44512
R376
P
D
S
S
D
A
D
R
L
E
R
F
F
D
S
Frog
Xenopus laevis
Q5XH30
450
51749
F431
V
Y
D
Q
N
D
L
F
T
E
D
E
K
K
R
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
R377
P
D
F
S
D
S
D
R
L
E
R
F
F
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
Y605
T
E
Q
T
E
M
N
Y
P
L
F
S
F
S
R
Honey Bee
Apis mellifera
XP_393739
477
54008
S453
I
A
E
N
I
I
P
S
T
T
S
F
T
G
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
R695
T
N
T
N
R
P
E
R
Y
L
R
V
R
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
T440
P
L
F
T
V
T
Q
T
H
T
A
I
N
Q
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
D489
G
G
R
A
E
A
I
D
E
V
E
T
L
E
S
Conservation
Percent
Protein Identity:
100
79.9
98.2
94.5
N.A.
90.3
89.5
N.A.
83.2
28.1
68.1
26.8
N.A.
26.5
30.3
N.A.
28
Protein Similarity:
100
79.9
98.9
97.3
N.A.
95.6
95.4
N.A.
88
42.5
82.7
46
N.A.
42
46.3
N.A.
41.4
P-Site Identity:
100
0
93.3
93.3
N.A.
66.6
66.6
N.A.
26.6
6.6
6.6
6.6
N.A.
6.6
13.3
N.A.
13.3
P-Site Similarity:
100
20
100
100
N.A.
80
73.3
N.A.
53.3
20
53.3
20
N.A.
26.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
0
7
0
14
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
14
7
7
47
14
14
7
0
34
14
0
7
14
0
% D
% Glu:
0
7
47
40
14
0
7
0
40
27
40
14
0
7
0
% E
% Phe:
0
0
14
0
0
0
34
14
0
0
14
20
20
0
14
% F
% Gly:
7
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
7
0
0
7
0
0
0
0
7
0
% H
% Ile:
14
0
0
0
7
7
7
0
0
0
0
7
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
27
47
14
0
% K
% Leu:
0
7
0
0
0
34
14
7
14
14
0
0
7
0
20
% L
% Met:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
27
0
14
7
0
7
0
0
0
0
0
7
14
7
% N
% Pro:
20
0
0
0
14
7
7
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
7
7
0
0
7
0
7
0
0
0
0
14
0
% Q
% Arg:
0
7
7
0
7
0
0
20
0
0
20
7
7
14
20
% R
% Ser:
0
14
7
14
0
7
0
34
7
7
7
7
0
7
34
% S
% Thr:
40
0
7
14
0
7
0
7
14
14
0
7
7
0
0
% T
% Val:
7
0
0
0
7
0
0
0
0
7
0
14
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
14
0
0
0
0
7
7
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _