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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4C
All Species:
31.82
Human Site:
S374
Identified Species:
50
UniProt:
Q96DT6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DT6
NP_116241.2
458
52497
S374
C
P
S
P
K
K
M
S
F
R
K
M
D
P
S
Chimpanzee
Pan troglodytes
XP_001159697
366
41520
N283
S
A
S
M
T
S
D
N
A
D
D
K
A
V
I
Rhesus Macaque
Macaca mulatta
XP_001086218
458
52551
S374
C
P
S
P
K
K
M
S
F
R
K
M
D
P
S
Dog
Lupus familis
XP_852273
458
52523
S374
C
P
S
P
K
K
M
S
F
R
K
M
D
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q811C2
458
52068
S374
C
P
S
P
K
K
M
S
F
R
K
M
D
P
S
Rat
Rattus norvegicus
NP_001101418
458
52091
S374
C
P
S
P
K
K
M
S
F
R
K
M
D
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
S374
C
P
S
P
K
K
M
S
F
R
K
M
D
P
S
Chicken
Gallus gallus
Q6PZ02
393
44512
I310
H
P
P
C
R
M
S
I
A
E
L
D
P
S
I
Frog
Xenopus laevis
Q5XH30
450
51749
S365
C
P
S
P
K
K
M
S
F
K
K
M
D
P
S
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
H311
Q
H
P
P
C
R
M
H
I
C
E
L
D
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
K539
C
K
S
P
R
K
L
K
A
S
K
M
D
P
S
Honey Bee
Apis mellifera
XP_393739
477
54008
L387
C
T
S
P
R
K
M
L
I
S
K
M
D
P
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
S629
C
M
S
P
R
K
M
S
I
S
K
M
D
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
V374
E
V
Q
Q
V
V
T
V
N
K
E
T
P
D
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
T423
Y
T
A
E
E
L
D
T
C
H
T
R
R
L
R
Conservation
Percent
Protein Identity:
100
79.9
98.2
94.5
N.A.
90.3
89.5
N.A.
83.2
28.1
68.1
26.8
N.A.
26.5
30.3
N.A.
28
Protein Similarity:
100
79.9
98.9
97.3
N.A.
95.6
95.4
N.A.
88
42.5
82.7
46
N.A.
42
46.3
N.A.
41.4
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
100
6.6
93.3
33.3
N.A.
60
66.6
N.A.
73.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
13.3
100
53.3
N.A.
73.3
73.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
0
0
20
0
0
0
7
0
0
% A
% Cys:
67
0
0
7
7
0
0
0
7
7
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
14
0
0
7
7
7
74
7
0
% D
% Glu:
7
0
0
7
7
0
0
0
0
7
14
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
47
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
7
7
0
0
0
0
0
7
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
20
0
0
0
0
0
14
% I
% Lys:
0
7
0
0
47
67
0
7
0
14
67
7
0
0
0
% K
% Leu:
0
0
0
0
0
7
7
7
0
0
7
7
0
7
0
% L
% Met:
0
7
0
7
0
7
67
0
0
0
0
67
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% N
% Pro:
0
54
14
74
0
0
0
0
0
0
0
0
14
74
0
% P
% Gln:
7
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
27
7
0
0
0
40
0
7
7
0
7
% R
% Ser:
7
0
74
0
0
7
7
54
0
20
0
0
0
7
74
% S
% Thr:
0
14
0
0
7
0
7
7
0
0
7
7
0
0
0
% T
% Val:
0
7
0
0
7
7
0
7
0
0
0
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _