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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4C
All Species:
17.27
Human Site:
S276
Identified Species:
27.14
UniProt:
Q96DT6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DT6
NP_116241.2
458
52497
S276
S
D
V
I
D
K
Q
S
A
S
M
T
S
D
N
Chimpanzee
Pan troglodytes
XP_001159697
366
41520
M191
K
Y
S
D
D
H
E
M
R
N
E
V
Y
H
R
Rhesus Macaque
Macaca mulatta
XP_001086218
458
52551
S276
C
D
V
I
D
K
Q
S
A
S
M
T
S
D
N
Dog
Lupus familis
XP_852273
458
52523
C276
S
D
V
I
D
K
Q
C
T
S
M
A
S
D
N
Cat
Felis silvestris
Mouse
Mus musculus
Q811C2
458
52068
T276
S
D
V
I
D
K
Q
T
D
S
V
T
A
G
D
Rat
Rattus norvegicus
NP_001101418
458
52091
T276
S
D
V
I
D
K
Q
T
D
S
V
T
A
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
R276
S
D
V
T
D
K
L
R
A
S
T
D
S
G
K
Chicken
Gallus gallus
Q6PZ02
393
44512
L218
G
V
R
D
K
L
S
L
W
K
P
L
V
L
L
Frog
Xenopus laevis
Q5XH30
450
51749
C272
A
D
V
Y
D
L
Q
C
N
K
G
N
E
K
A
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
A219
A
L
A
E
E
E
T
A
L
W
K
P
L
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
S420
Q
D
I
E
D
Q
C
S
I
P
E
P
A
P
K
Honey Bee
Apis mellifera
XP_393739
477
54008
Q293
Q
D
I
E
N
V
C
Q
T
S
D
G
K
W
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
S533
Q
D
V
I
D
L
T
S
L
P
V
R
T
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
S275
A
V
H
I
V
S
G
S
E
D
G
E
R
G
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
F329
P
D
V
Y
E
D
S
F
M
A
V
A
N
P
D
Conservation
Percent
Protein Identity:
100
79.9
98.2
94.5
N.A.
90.3
89.5
N.A.
83.2
28.1
68.1
26.8
N.A.
26.5
30.3
N.A.
28
Protein Similarity:
100
79.9
98.9
97.3
N.A.
95.6
95.4
N.A.
88
42.5
82.7
46
N.A.
42
46.3
N.A.
41.4
P-Site Identity:
100
6.6
93.3
80
N.A.
60
60
N.A.
53.3
0
26.6
0
N.A.
20
13.3
N.A.
40
P-Site Similarity:
100
20
93.3
80
N.A.
86.6
86.6
N.A.
53.3
0
33.3
26.6
N.A.
40
26.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
7
0
0
0
0
7
20
7
0
14
20
0
7
% A
% Cys:
7
0
0
0
0
0
14
14
0
0
0
0
0
0
0
% C
% Asp:
0
74
0
14
67
7
0
0
14
7
7
7
0
27
20
% D
% Glu:
0
0
0
20
14
7
7
0
7
0
14
7
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
7
0
0
0
14
7
0
27
7
% G
% His:
0
0
7
0
0
7
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
14
47
0
0
0
0
7
0
0
0
0
0
0
% I
% Lys:
7
0
0
0
7
40
0
0
0
14
7
0
7
7
20
% K
% Leu:
0
7
0
0
0
20
7
7
14
0
0
7
7
7
14
% L
% Met:
0
0
0
0
0
0
0
7
7
0
20
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
7
7
0
7
7
0
20
% N
% Pro:
7
0
0
0
0
0
0
0
0
14
7
14
0
14
7
% P
% Gln:
20
0
0
0
0
7
40
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
0
0
7
7
0
0
7
7
0
7
% R
% Ser:
34
0
7
0
0
7
14
34
0
47
0
0
27
0
0
% S
% Thr:
0
0
0
7
0
0
14
14
14
0
7
27
7
0
0
% T
% Val:
0
14
60
0
7
7
0
0
0
0
27
7
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
7
0
0
0
7
0
% W
% Tyr:
0
7
0
14
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _