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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4C
All Species:
17.58
Human Site:
S166
Identified Species:
27.62
UniProt:
Q96DT6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DT6
NP_116241.2
458
52497
S166
A
S
F
E
A
S
L
S
G
E
R
E
F
K
T
Chimpanzee
Pan troglodytes
XP_001159697
366
41520
Y91
I
S
R
I
W
L
T
Y
R
E
E
F
P
Q
I
Rhesus Macaque
Macaca mulatta
XP_001086218
458
52551
S166
A
S
F
E
A
S
L
S
G
E
R
E
L
K
T
Dog
Lupus familis
XP_852273
458
52523
S166
A
S
F
E
A
S
L
S
G
E
S
E
L
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q811C2
458
52068
S166
A
S
F
E
A
S
L
S
G
D
R
E
L
R
T
Rat
Rattus norvegicus
NP_001101418
458
52091
S166
A
S
F
E
A
S
L
S
G
E
R
E
L
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
V166
A
S
F
E
A
S
W
V
G
E
R
D
P
R
P
Chicken
Gallus gallus
Q6PZ02
393
44512
K118
L
N
A
F
I
D
K
K
D
S
Y
Y
S
I
H
Frog
Xenopus laevis
Q5XH30
450
51749
P167
P
S
L
E
K
S
S
P
E
N
E
E
Y
V
S
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
K119
L
N
A
F
I
D
K
K
D
S
Y
Y
S
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
P229
S
T
S
T
S
L
Y
P
A
L
N
P
Q
Q
I
Honey Bee
Apis mellifera
XP_393739
477
54008
L181
Q
M
M
L
A
Q
A
L
V
C
H
F
L
G
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
M421
C
M
L
R
S
G
Q
M
M
L
A
H
S
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
I172
D
V
N
W
G
C
M
I
R
S
S
Q
M
L
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
C226
S
S
D
T
G
W
G
C
M
I
R
S
G
Q
S
Conservation
Percent
Protein Identity:
100
79.9
98.2
94.5
N.A.
90.3
89.5
N.A.
83.2
28.1
68.1
26.8
N.A.
26.5
30.3
N.A.
28
Protein Similarity:
100
79.9
98.9
97.3
N.A.
95.6
95.4
N.A.
88
42.5
82.7
46
N.A.
42
46.3
N.A.
41.4
P-Site Identity:
100
13.3
93.3
86.6
N.A.
80
86.6
N.A.
60
0
26.6
0
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
20
93.3
86.6
N.A.
93.3
93.3
N.A.
73.3
6.6
40
6.6
N.A.
26.6
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
14
0
47
0
7
0
7
0
7
0
0
0
0
% A
% Cys:
7
0
0
0
0
7
0
7
0
7
0
0
0
0
0
% C
% Asp:
7
0
7
0
0
14
0
0
14
7
0
7
0
0
0
% D
% Glu:
0
0
0
47
0
0
0
0
7
40
14
40
0
0
0
% E
% Phe:
0
0
40
14
0
0
0
0
0
0
0
14
7
0
7
% F
% Gly:
0
0
0
0
14
7
7
0
40
0
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
14
% H
% Ile:
7
0
0
7
14
0
0
7
0
7
0
0
0
14
20
% I
% Lys:
0
0
0
0
7
0
14
14
0
0
0
0
0
20
0
% K
% Leu:
14
0
14
7
0
14
34
7
0
14
0
0
34
14
0
% L
% Met:
0
14
7
0
0
0
7
7
14
0
0
0
7
0
0
% M
% Asn:
0
14
7
0
0
0
0
0
0
7
7
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
0
14
0
0
0
7
14
0
7
% P
% Gln:
7
0
0
0
0
7
7
0
0
0
0
7
7
20
0
% Q
% Arg:
0
0
7
7
0
0
0
0
14
0
40
0
0
20
7
% R
% Ser:
14
60
7
0
14
47
7
34
0
20
14
7
20
0
14
% S
% Thr:
0
7
0
14
0
0
7
0
0
0
0
0
0
0
34
% T
% Val:
0
7
0
0
0
0
0
7
7
0
0
0
0
7
0
% V
% Trp:
0
0
0
7
7
7
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
7
0
0
14
14
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _