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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATG4C All Species: 26.67
Human Site: S160 Identified Species: 41.9
UniProt: Q96DT6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96DT6 NP_116241.2 458 52497 S160 T V K K F T A S F E A S L S G
Chimpanzee Pan troglodytes XP_001159697 366 41520 S85 E F R K D F I S R I W L T Y R
Rhesus Macaque Macaca mulatta XP_001086218 458 52551 S160 T V K K F T A S F E A S L S G
Dog Lupus familis XP_852273 458 52523 S160 T V K K F T A S F E A S L S G
Cat Felis silvestris
Mouse Mus musculus Q811C2 458 52068 S160 T V K K F T A S F E A S L S G
Rat Rattus norvegicus NP_001101418 458 52091 S160 T I H K F T A S F E A S L S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514370 459 52127 S160 T V K K L T A S F E A S W V G
Chicken Gallus gallus Q6PZ02 393 44512 N112 D N Y F S V L N A F I D K K D
Frog Xenopus laevis Q5XH30 450 51749 S161 T A R K L D P S L E K S S P E
Zebra Danio Brachydanio rerio Q6DG88 394 44435 N113 P E Y V S I L N A F I D K K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650452 668 74736 T223 D S I Q A T S T S T S L Y P A
Honey Bee Apis mellifera XP_393739 477 54008 M175 C M L R S G Q M M L A Q A L V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786847 723 81931 M415 S D C G W G C M L R S G Q M M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8S929 467 51510 V166 D T T Y T S D V N W G C M I R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S3X7 506 55337 S220 S D L T G F S S D T G W G C M
Conservation
Percent
Protein Identity: 100 79.9 98.2 94.5 N.A. 90.3 89.5 N.A. 83.2 28.1 68.1 26.8 N.A. 26.5 30.3 N.A. 28
Protein Similarity: 100 79.9 98.9 97.3 N.A. 95.6 95.4 N.A. 88 42.5 82.7 46 N.A. 42 46.3 N.A. 41.4
P-Site Identity: 100 13.3 100 100 N.A. 100 86.6 N.A. 80 0 33.3 0 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 20 100 100 N.A. 100 93.3 N.A. 80 6.6 40 6.6 N.A. 33.3 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 22.7 N.A. 21.5
Protein Similarity: N.A. N.A. N.A. 41.1 N.A. 39.3
P-Site Identity: N.A. N.A. N.A. 0 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 7 0 40 0 14 0 47 0 7 0 7 % A
% Cys: 7 0 7 0 0 0 7 0 0 0 0 7 0 7 0 % C
% Asp: 20 14 0 0 7 7 7 0 7 0 0 14 0 0 14 % D
% Glu: 7 7 0 0 0 0 0 0 0 47 0 0 0 0 7 % E
% Phe: 0 7 0 7 34 14 0 0 40 14 0 0 0 0 0 % F
% Gly: 0 0 0 7 7 14 0 0 0 0 14 7 7 0 40 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 7 0 0 7 7 0 0 7 14 0 0 7 0 % I
% Lys: 0 0 34 54 0 0 0 0 0 0 7 0 14 14 0 % K
% Leu: 0 0 14 0 14 0 14 0 14 7 0 14 34 7 0 % L
% Met: 0 7 0 0 0 0 0 14 7 0 0 0 7 7 14 % M
% Asn: 0 7 0 0 0 0 0 14 7 0 0 0 0 0 0 % N
% Pro: 7 0 0 0 0 0 7 0 0 0 0 0 0 14 0 % P
% Gln: 0 0 0 7 0 0 7 0 0 0 0 7 7 0 0 % Q
% Arg: 0 0 14 7 0 0 0 0 7 7 0 0 0 0 14 % R
% Ser: 14 7 0 0 20 7 14 60 7 0 14 47 7 34 0 % S
% Thr: 47 7 7 7 7 47 0 7 0 14 0 0 7 0 0 % T
% Val: 0 34 0 7 0 7 0 7 0 0 0 0 0 7 7 % V
% Trp: 0 0 0 0 7 0 0 0 0 7 7 7 7 0 0 % W
% Tyr: 0 0 14 7 0 0 0 0 0 0 0 0 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _