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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C18orf8
All Species:
23.03
Human Site:
T186
Identified Species:
46.06
UniProt:
Q96DM3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DM3
NP_037458.3
657
74975
T186
P
F
H
F
R
A
G
T
M
S
K
L
P
K
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094510
653
74492
L186
S
F
R
F
I
P
R
L
P
K
F
E
I
E
L
Dog
Lupus familis
XP_848531
769
86434
T298
P
F
Y
F
R
A
G
T
M
S
K
L
P
K
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC42
657
74904
T186
P
F
H
F
R
A
G
T
M
S
K
L
P
K
F
Rat
Rattus norvegicus
NP_001009638
657
74859
T186
P
F
Y
F
K
A
G
T
M
S
K
L
P
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419161
689
77249
T218
P
F
Y
F
K
S
G
T
M
S
K
L
S
K
F
Frog
Xenopus laevis
NP_001108247
653
74516
T185
P
F
Y
F
R
A
G
T
V
S
K
M
T
K
F
Zebra Danio
Brachydanio rerio
NP_001008621
449
50559
E29
V
N
N
V
F
F
D
E
A
N
K
Q
V
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648047
632
70874
S179
L
C
T
S
E
G
N
S
L
I
P
V
L
V
K
Honey Bee
Apis mellifera
XP_396084
669
76030
N192
T
L
H
V
T
P
G
N
L
H
K
L
T
K
F
Nematode Worm
Caenorhab. elegans
NP_503392
622
69639
E172
I
S
K
E
N
F
L
E
K
D
A
A
I
A
T
Sea Urchin
Strong. purpuratus
XP_001204062
489
55593
D70
N
E
I
I
F
I
T
D
H
G
L
E
L
Y
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.9
79.1
N.A.
94.9
95.1
N.A.
N.A.
85
81.4
51.2
N.A.
35.6
47.3
27.7
37.6
Protein Similarity:
100
N.A.
96.1
82.8
N.A.
98
97.8
N.A.
N.A.
90.2
90.2
60.4
N.A.
59.6
66.5
47.3
51.9
P-Site Identity:
100
N.A.
13.3
93.3
N.A.
100
86.6
N.A.
N.A.
73.3
73.3
6.6
N.A.
0
40
0
0
P-Site Similarity:
100
N.A.
20
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
20
N.A.
20
46.6
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
42
0
0
9
0
9
9
0
9
9
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
9
0
9
0
0
0
0
0
% D
% Glu:
0
9
0
9
9
0
0
17
0
0
0
17
0
9
0
% E
% Phe:
0
59
0
59
17
17
0
0
0
0
9
0
0
9
59
% F
% Gly:
0
0
0
0
0
9
59
0
0
9
0
0
0
0
0
% G
% His:
0
0
25
0
0
0
0
0
9
9
0
0
0
0
0
% H
% Ile:
9
0
9
9
9
9
0
0
0
9
0
0
17
0
0
% I
% Lys:
0
0
9
0
17
0
0
0
9
9
67
0
0
59
9
% K
% Leu:
9
9
0
0
0
0
9
9
17
0
9
50
17
0
9
% L
% Met:
0
0
0
0
0
0
0
0
42
0
0
9
0
0
0
% M
% Asn:
9
9
9
0
9
0
9
9
0
9
0
0
0
0
0
% N
% Pro:
50
0
0
0
0
17
0
0
9
0
9
0
34
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% Q
% Arg:
0
0
9
0
34
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
9
0
9
0
9
0
50
0
0
9
0
0
% S
% Thr:
9
0
9
0
9
0
9
50
0
0
0
0
17
0
9
% T
% Val:
9
0
0
17
0
0
0
0
9
0
0
9
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
34
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _