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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2M1
All Species:
28.79
Human Site:
S236
Identified Species:
48.72
UniProt:
Q96CW1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CW1
NP_001020376.1
435
49655
S236
T
A
D
E
T
S
K
S
G
K
Q
S
I
A
I
Chimpanzee
Pan troglodytes
XP_001143960
424
48467
S229
K
Q
G
K
G
T
Q
S
I
A
I
D
D
C
T
Rhesus Macaque
Macaca mulatta
XP_001102323
427
48656
G228
I
V
S
G
A
S
L
G
G
K
Q
S
I
A
I
Dog
Lupus familis
XP_858405
437
49906
S238
T
A
D
E
T
S
K
S
G
K
Q
S
I
A
I
Cat
Felis silvestris
Mouse
Mus musculus
P35585
423
48524
S228
D
N
T
G
R
G
K
S
K
S
V
E
L
E
D
Rat
Rattus norvegicus
P84092
435
49636
S236
T
A
D
E
T
S
K
S
G
K
Q
S
I
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMP6
433
49371
S234
T
A
D
E
T
G
K
S
G
K
Q
S
I
A
I
Frog
Xenopus laevis
Q801Q8
435
49666
T236
T
A
D
E
T
G
K
T
G
K
Q
S
I
A
I
Zebra Danio
Brachydanio rerio
Q7ZW98
436
49724
S237
T
T
D
D
T
G
K
S
G
K
Q
S
I
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732744
437
49837
S238
S
E
A
E
T
S
R
S
G
K
P
V
V
V
I
Honey Bee
Apis mellifera
XP_391965
442
49946
S243
D
D
P
T
G
A
R
S
G
K
P
V
V
V
I
Nematode Worm
Caenorhab. elegans
P35603
441
50282
A240
G
S
D
D
P
N
K
A
S
R
A
A
V
A
I
Sea Urchin
Strong. purpuratus
XP_801936
438
49913
K239
G
K
G
D
D
P
A
K
S
K
S
S
I
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
K265
T
S
S
S
A
T
N
K
K
K
V
N
I
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
96.5
99.5
N.A.
40
100
N.A.
N.A.
99
99
97.9
N.A.
87.4
85.2
81.1
86.5
Protein Similarity:
100
97.4
96.7
99.5
N.A.
61.3
100
N.A.
N.A.
99
99.5
98.6
N.A.
94.5
92.7
91.1
94.5
P-Site Identity:
100
6.6
53.3
100
N.A.
13.3
100
N.A.
N.A.
93.3
86.6
80
N.A.
46.6
26.6
26.6
33.3
P-Site Similarity:
100
26.6
53.3
100
N.A.
20
100
N.A.
N.A.
93.3
93.3
86.6
N.A.
66.6
46.6
73.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
57.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
36
8
0
15
8
8
8
0
8
8
8
0
65
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
15
8
50
22
8
0
0
0
0
0
0
8
8
0
8
% D
% Glu:
0
8
0
43
0
0
0
0
0
0
0
8
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
0
15
15
15
29
0
8
65
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
0
8
0
65
0
79
% I
% Lys:
8
8
0
8
0
0
58
15
15
79
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
8
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
8
0
8
8
0
0
0
0
15
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
50
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
15
0
0
8
0
0
0
0
0
% R
% Ser:
8
15
15
8
0
36
0
65
15
8
8
58
0
0
0
% S
% Thr:
50
8
8
8
50
15
0
8
0
0
0
0
0
0
8
% T
% Val:
0
8
0
0
0
0
0
0
0
0
15
15
22
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _