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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL8
All Species:
30.91
Human Site:
Y357
Identified Species:
68
UniProt:
Q96CD0
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CD0
NP_060848.2
374
40516
Y357
H
C
P
R
L
R
T
Y
T
L
K
L
T
R
E
Chimpanzee
Pan troglodytes
XP_001161314
374
40542
Y357
H
C
P
R
L
R
T
Y
T
L
K
L
T
R
E
Rhesus Macaque
Macaca mulatta
XP_001086810
452
48847
Y357
H
C
P
R
L
R
T
Y
T
L
K
L
T
R
E
Dog
Lupus familis
XP_853996
374
40940
Y357
H
C
P
R
L
R
S
Y
T
L
K
L
T
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIG9
374
41126
Y357
H
C
P
R
L
R
S
Y
T
L
K
L
K
R
E
Rat
Rattus norvegicus
NP_001102598
374
41234
Y357
H
C
P
R
L
R
S
Y
T
L
K
L
K
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414068
379
43704
Y362
H
C
P
H
L
K
Q
Y
T
L
K
V
T
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001032499
334
37432
Y317
N
C
P
N
L
C
R
Y
T
L
K
T
H
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393659
481
52936
N459
G
C
T
R
I
S
T
N
G
L
E
R
I
M
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797608
410
46823
S379
L
C
P
N
L
E
E
S
T
L
K
T
E
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZPE4
317
36464
D268
C
C
S
D
Y
F
S
D
G
S
D
Y
L
A
W
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
78.7
84.4
N.A.
78.6
78.3
N.A.
N.A.
41.4
N.A.
35.8
N.A.
N.A.
20.1
N.A.
26.1
Protein Similarity:
100
99.4
79.8
89
N.A.
83.9
83.9
N.A.
N.A.
61.4
N.A.
49.2
N.A.
N.A.
35.1
N.A.
39.5
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
66.6
N.A.
46.6
N.A.
N.A.
26.6
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
N.A.
60
N.A.
N.A.
46.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
10
100
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
0
10
0
0
10
10
% D
% Glu:
0
0
0
0
0
10
10
0
0
0
10
0
10
0
64
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
19
0
0
0
0
0
10
% G
% His:
64
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
82
0
19
19
10
% K
% Leu:
10
0
0
0
82
0
0
0
0
91
0
55
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
10
0
0
19
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
82
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
64
0
55
10
0
0
0
0
10
0
55
0
% R
% Ser:
0
0
10
0
0
10
37
10
0
10
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
37
0
82
0
0
19
46
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
10
0
0
73
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _