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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL8
All Species:
25.45
Human Site:
S81
Identified Species:
56
UniProt:
Q96CD0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CD0
NP_060848.2
374
40516
S81
L
R
L
E
F
E
P
S
R
K
P
S
R
R
A
Chimpanzee
Pan troglodytes
XP_001161314
374
40542
S81
L
R
L
E
F
E
P
S
R
K
P
S
R
R
A
Rhesus Macaque
Macaca mulatta
XP_001086810
452
48847
S81
L
R
L
E
F
E
P
S
R
E
V
S
R
R
A
Dog
Lupus familis
XP_853996
374
40940
S81
L
Q
L
E
F
E
P
S
R
E
P
S
R
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIG9
374
41126
S81
L
R
L
E
Y
E
P
S
K
K
P
S
R
G
T
Rat
Rattus norvegicus
NP_001102598
374
41234
S81
L
S
L
E
Y
E
P
S
K
K
P
S
R
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414068
379
43704
S85
L
K
I
R
F
D
Q
S
K
E
V
N
R
R
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001032499
334
37432
A73
G
L
S
I
C
C
V
A
N
T
P
L
F
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393659
481
52936
L173
R
R
G
L
G
D
V
L
K
G
V
P
N
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797608
410
46823
K96
V
C
V
V
L
N
Q
K
G
E
D
N
R
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZPE4
317
36464
S66
W
S
N
R
F
H
Q
S
D
H
L
D
R
M
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
78.7
84.4
N.A.
78.6
78.3
N.A.
N.A.
41.4
N.A.
35.8
N.A.
N.A.
20.1
N.A.
26.1
Protein Similarity:
100
99.4
79.8
89
N.A.
83.9
83.9
N.A.
N.A.
61.4
N.A.
49.2
N.A.
N.A.
35.1
N.A.
39.5
P-Site Identity:
100
100
86.6
86.6
N.A.
73.3
73.3
N.A.
N.A.
33.3
N.A.
13.3
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
93.3
100
N.A.
86.6
86.6
N.A.
N.A.
73.3
N.A.
20
N.A.
N.A.
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
46
% A
% Cys:
0
10
0
0
10
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
19
0
0
10
0
10
10
0
0
0
% D
% Glu:
0
0
0
55
0
55
0
0
0
37
0
0
0
0
10
% E
% Phe:
0
0
0
0
55
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
0
10
0
10
0
0
0
10
10
0
0
0
10
0
% G
% His:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
10
37
37
0
0
0
0
0
% K
% Leu:
64
10
55
10
10
0
0
10
0
0
10
10
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
10
0
0
10
0
0
19
10
0
19
% N
% Pro:
0
0
0
0
0
0
55
0
0
0
55
10
0
0
0
% P
% Gln:
0
10
0
0
0
0
28
0
0
0
0
0
0
0
0
% Q
% Arg:
10
46
0
19
0
0
0
0
37
0
0
0
82
64
0
% R
% Ser:
0
19
10
0
0
0
0
73
0
0
0
55
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
19
% T
% Val:
10
0
10
10
0
0
19
0
0
0
28
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
19
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _