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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL8
All Species:
0
Human Site:
S146
Identified Species:
0
UniProt:
Q96CD0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CD0
NP_060848.2
374
40516
S146
H
L
D
L
R
R
L
S
F
T
L
D
D
A
L
Chimpanzee
Pan troglodytes
XP_001161314
374
40542
P146
H
L
D
L
R
R
L
P
F
T
L
D
D
A
L
Rhesus Macaque
Macaca mulatta
XP_001086810
452
48847
P146
H
L
D
L
R
R
L
P
F
T
L
D
D
A
L
Dog
Lupus familis
XP_853996
374
40940
P146
H
L
D
L
R
R
L
P
F
T
L
D
D
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIG9
374
41126
P146
H
L
D
L
R
H
L
P
Y
T
L
D
D
T
L
Rat
Rattus norvegicus
NP_001102598
374
41234
P146
H
L
D
L
R
H
L
P
Y
T
V
D
D
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414068
379
43704
P152
H
V
D
F
R
N
M
P
F
T
L
D
G
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001032499
334
37432
P107
I
F
D
L
K
G
V
P
F
T
L
S
D
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393659
481
52936
V217
N
L
S
L
C
K
Q
V
S
D
I
S
L
G
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797608
410
46823
A169
K
I
D
L
S
Q
L
A
I
S
I
S
D
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZPE4
317
36464
A105
F
S
F
I
A
Q
H
A
G
S
L
K
T
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
78.7
84.4
N.A.
78.6
78.3
N.A.
N.A.
41.4
N.A.
35.8
N.A.
N.A.
20.1
N.A.
26.1
Protein Similarity:
100
99.4
79.8
89
N.A.
83.9
83.9
N.A.
N.A.
61.4
N.A.
49.2
N.A.
N.A.
35.1
N.A.
39.5
P-Site Identity:
100
93.3
93.3
93.3
N.A.
73.3
66.6
N.A.
N.A.
53.3
N.A.
40
N.A.
N.A.
13.3
N.A.
26.6
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
80
80
N.A.
N.A.
66.6
N.A.
60
N.A.
N.A.
33.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
19
0
0
0
0
0
37
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
82
0
0
0
0
0
0
10
0
64
73
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
10
10
10
10
0
0
0
0
55
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
10
0
0
10
0
0
0
10
10
0
% G
% His:
64
0
0
0
0
19
10
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
10
0
0
0
0
10
0
19
0
0
0
0
% I
% Lys:
10
0
0
0
10
10
0
0
0
0
0
10
0
0
10
% K
% Leu:
0
64
0
82
0
0
64
0
0
0
73
0
10
10
64
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
64
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
19
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
64
37
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
10
10
0
10
0
0
10
10
19
0
28
0
19
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
73
0
0
10
19
10
% T
% Val:
0
10
0
0
0
0
10
10
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _