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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSUN4 All Species: 37.58
Human Site: Y376 Identified Species: 63.59
UniProt: Q96CB9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CB9 NP_950245.2 384 43089 Y376 M A N F G P M Y F C K M R R L
Chimpanzee Pan troglodytes XP_513142 833 91470 W785 R G Y F G D I W D K M L Q K G
Rhesus Macaque Macaca mulatta XP_001108301 384 43099 Y376 M A N F G P M Y F C K M H R L
Dog Lupus familis XP_853047 384 43059 Y376 L A N F G P M Y F C K M C R L
Cat Felis silvestris
Mouse Mus musculus Q9CZ57 381 42835 Y373 M V N F G P M Y F C K L H R L
Rat Rattus norvegicus NP_001100148 381 42594 Y373 M A N F G P M Y F C K L H R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518738 248 26969 C241 A R R D H L R C L M Q R W A D
Chicken Gallus gallus XP_422449 404 44758 Y397 T A N F G P M Y F C K L R R A
Frog Xenopus laevis Q5M7E3 406 46042 F398 T A N F G P M F F C K L L R I
Zebra Danio Brachydanio rerio Q4KMK0 367 41244 Y359 G K T W G P M Y V S Q L K K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608573 503 57519 Y495 P A N F G P M Y F S K I T R N
Honey Bee Apis mellifera XP_394395 493 56346 Y485 H N N W G P M Y F C K I V K V
Nematode Worm Caenorhab. elegans NP_490958 465 51501 Y457 P S N F G P M Y I C K L T R L
Sea Urchin Strong. purpuratus XP_792601 513 57508 Y505 S A N Y G P M Y F S R L I R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.7 96.6 84.9 N.A. 85.9 83.5 N.A. 38.5 61.1 59.3 35.1 N.A. 32.5 32.4 31.3 35.4
Protein Similarity: 100 45.9 98.4 91.4 N.A. 91.9 90.6 N.A. 47.9 74.5 72.6 54.1 N.A. 48.3 47.6 46.8 49.3
P-Site Identity: 100 13.3 93.3 86.6 N.A. 80 80 N.A. 0 80 66.6 26.6 N.A. 66.6 53.3 66.6 53.3
P-Site Similarity: 100 46.6 93.3 93.3 N.A. 86.6 93.3 N.A. 6.6 86.6 86.6 66.6 N.A. 73.3 80 80 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 58 0 0 0 0 0 0 0 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 65 0 0 8 0 0 % C
% Asp: 0 0 0 8 0 8 0 0 8 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 72 0 0 0 8 72 0 0 0 0 0 0 % F
% Gly: 8 8 0 0 93 0 0 0 0 0 0 0 0 0 8 % G
% His: 8 0 0 0 8 0 0 0 0 0 0 0 22 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 8 0 0 15 8 0 15 % I
% Lys: 0 8 0 0 0 0 0 0 0 8 72 0 8 22 0 % K
% Leu: 8 0 0 0 0 8 0 0 8 0 0 58 8 0 36 % L
% Met: 29 0 0 0 0 0 86 0 0 8 8 22 0 0 0 % M
% Asn: 0 8 79 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 15 0 0 0 0 86 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 15 0 8 0 0 % Q
% Arg: 8 8 8 0 0 0 8 0 0 0 8 8 15 72 0 % R
% Ser: 8 8 0 0 0 0 0 0 0 22 0 0 0 0 0 % S
% Thr: 15 0 8 0 0 0 0 0 0 0 0 0 15 0 8 % T
% Val: 0 8 0 0 0 0 0 0 8 0 0 0 8 0 15 % V
% Trp: 0 0 0 15 0 0 0 8 0 0 0 0 8 0 0 % W
% Tyr: 0 0 8 8 0 0 0 79 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _