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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSUN4 All Species: 24.85
Human Site: T133 Identified Species: 42.05
UniProt: Q96CB9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CB9 NP_950245.2 384 43089 T133 S P N L R C F T F D R G D I S
Chimpanzee Pan troglodytes XP_513142 833 91470 T133 S P N L R C F T F D R G D I S
Rhesus Macaque Macaca mulatta XP_001108301 384 43099 T133 S P N L R C F T F A R G D V S
Dog Lupus familis XP_853047 384 43059 T133 S P N L R C F T F A R G D V S
Cat Felis silvestris
Mouse Mus musculus Q9CZ57 381 42835 R133 L R C F T F S R G D V S R F P
Rat Rattus norvegicus NP_001100148 381 42594 K133 L R C F T F S K G D V S R F P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518738 248 26969 N20 A L Q N F D V N Y S V Q F G D
Chicken Gallus gallus XP_422449 404 44758 T135 G S G G D G T T L P T E T S P
Frog Xenopus laevis Q5M7E3 406 46042 T155 N S K L T C F T F S R G D I S
Zebra Danio Brachydanio rerio Q4KMK0 367 41244 T133 P D P V R I P T Q S H H T G W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608573 503 57519 T250 P E H L S L Y T Y E M G N C S
Honey Bee Apis mellifera XP_394395 493 56346 T243 P E H L H V Y T F E R D N Y T
Nematode Worm Caenorhab. elegans NP_490958 465 51501 S212 P Q A L H V R S F D R A V L L
Sea Urchin Strong. purpuratus XP_792601 513 57508 E135 D T P E D A P E D A P E N G N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.7 96.6 84.9 N.A. 85.9 83.5 N.A. 38.5 61.1 59.3 35.1 N.A. 32.5 32.4 31.3 35.4
Protein Similarity: 100 45.9 98.4 91.4 N.A. 91.9 90.6 N.A. 47.9 74.5 72.6 54.1 N.A. 48.3 47.6 46.8 49.3
P-Site Identity: 100 100 86.6 86.6 N.A. 6.6 6.6 N.A. 0 6.6 66.6 13.3 N.A. 26.6 26.6 26.6 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 6.6 6.6 N.A. 13.3 6.6 73.3 20 N.A. 60 60 40 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 8 0 0 0 22 0 8 0 0 0 % A
% Cys: 0 0 15 0 0 36 0 0 0 0 0 0 0 8 0 % C
% Asp: 8 8 0 0 15 8 0 0 8 36 0 8 36 0 8 % D
% Glu: 0 15 0 8 0 0 0 8 0 15 0 15 0 0 0 % E
% Phe: 0 0 0 15 8 15 36 0 50 0 0 0 8 15 0 % F
% Gly: 8 0 8 8 0 8 0 0 15 0 0 43 0 22 0 % G
% His: 0 0 15 0 15 0 0 0 0 0 8 8 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 22 0 % I
% Lys: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % K
% Leu: 15 8 0 58 0 8 0 0 8 0 0 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 8 0 29 8 0 0 0 8 0 0 0 0 22 0 8 % N
% Pro: 29 29 15 0 0 0 15 0 0 8 8 0 0 0 22 % P
% Gln: 0 8 8 0 0 0 0 0 8 0 0 8 0 0 0 % Q
% Arg: 0 15 0 0 36 0 8 8 0 0 50 0 15 0 0 % R
% Ser: 29 15 0 0 8 0 15 8 0 22 0 15 0 8 43 % S
% Thr: 0 8 0 0 22 0 8 65 0 0 8 0 15 0 8 % T
% Val: 0 0 0 8 0 15 8 0 0 0 22 0 8 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 15 0 15 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _