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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSUN4 All Species: 16.36
Human Site: S122 Identified Species: 27.69
UniProt: Q96CB9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CB9 NP_950245.2 384 43089 S122 S A A P S P A S W A C S P N L
Chimpanzee Pan troglodytes XP_513142 833 91470 S122 S A A P S P A S W A C S P N L
Rhesus Macaque Macaca mulatta XP_001108301 384 43099 S122 S A A P S P A S W A C S P N L
Dog Lupus familis XP_853047 384 43059 S122 T T T P P Q A S G A Y S P N L
Cat Felis silvestris
Mouse Mus musculus Q9CZ57 381 42835 C122 S P T P S L D C S P N L R C F
Rat Rattus norvegicus NP_001100148 381 42594 C122 S P T L S L D C S P N L R C F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518738 248 26969 S9 T T D F R F P S T K L A L Q N
Chicken Gallus gallus XP_422449 404 44758 T124 V G G E R R K T S L E G S G G
Frog Xenopus laevis Q5M7E3 406 46042 S144 T Q A T N L L S S L S N S K L
Zebra Danio Brachydanio rerio Q4KMK0 367 41244 C122 T A D I P L Q C F I H P D P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608573 503 57519 S239 L A I E P E P S F H Y P E H L
Honey Bee Apis mellifera XP_394395 493 56346 V232 V S V E N E H V L P F P E H L
Nematode Worm Caenorhab. elegans NP_490958 465 51501 F201 R I P K R D H F F Y Y P Q A L
Sea Urchin Strong. purpuratus XP_792601 513 57508 G124 T K P G R L R G G V E D T P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.7 96.6 84.9 N.A. 85.9 83.5 N.A. 38.5 61.1 59.3 35.1 N.A. 32.5 32.4 31.3 35.4
Protein Similarity: 100 45.9 98.4 91.4 N.A. 91.9 90.6 N.A. 47.9 74.5 72.6 54.1 N.A. 48.3 47.6 46.8 49.3
P-Site Identity: 100 100 100 53.3 N.A. 20 13.3 N.A. 6.6 0 20 6.6 N.A. 20 6.6 6.6 0
P-Site Similarity: 100 100 100 60 N.A. 20 13.3 N.A. 20 6.6 40 26.6 N.A. 33.3 26.6 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 36 29 0 0 0 29 0 0 29 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 22 0 0 22 0 0 15 0 % C
% Asp: 0 0 15 0 0 8 15 0 0 0 0 8 8 0 0 % D
% Glu: 0 0 0 22 0 15 0 0 0 0 15 0 15 0 8 % E
% Phe: 0 0 0 8 0 8 0 8 22 0 8 0 0 0 15 % F
% Gly: 0 8 8 8 0 0 0 8 15 0 0 8 0 8 8 % G
% His: 0 0 0 0 0 0 15 0 0 8 8 0 0 15 0 % H
% Ile: 0 8 8 8 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 8 0 8 0 0 8 0 0 8 0 0 0 8 0 % K
% Leu: 8 0 0 8 0 36 8 0 8 15 8 15 8 0 58 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 15 0 0 0 0 0 15 8 0 29 8 % N
% Pro: 0 15 15 36 22 22 15 0 0 22 0 29 29 15 0 % P
% Gln: 0 8 0 0 0 8 8 0 0 0 0 0 8 8 0 % Q
% Arg: 8 0 0 0 29 8 8 0 0 0 0 0 15 0 0 % R
% Ser: 36 8 0 0 36 0 0 50 29 0 8 29 15 0 0 % S
% Thr: 36 15 22 8 0 0 0 8 8 0 0 0 8 0 0 % T
% Val: 15 0 8 0 0 0 0 8 0 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 22 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 22 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _