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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSUN4 All Species: 11.21
Human Site: S119 Identified Species: 18.97
UniProt: Q96CB9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CB9 NP_950245.2 384 43089 S119 G G Q S A A P S P A S W A C S
Chimpanzee Pan troglodytes XP_513142 833 91470 S119 G G Q S A A P S P A S W A C S
Rhesus Macaque Macaca mulatta XP_001108301 384 43099 S119 G G Q S A A P S P A S W A C S
Dog Lupus familis XP_853047 384 43059 P119 S G Q T T T P P Q A S G A Y S
Cat Felis silvestris
Mouse Mus musculus Q9CZ57 381 42835 S119 S G L S P T P S L D C S P N L
Rat Rattus norvegicus NP_001100148 381 42594 S119 S G L S P T L S L D C S P N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518738 248 26969
Chicken Gallus gallus XP_422449 404 44758 R121 S A G V G G E R R K T S L E G
Frog Xenopus laevis Q5M7E3 406 46042 N141 A E Q T Q A T N L L S S L S N
Zebra Danio Brachydanio rerio Q4KMK0 367 41244 P119 H S Q T A D I P L Q C F I H P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608573 503 57519 P236 D F P L A I E P E P S F H Y P
Honey Bee Apis mellifera XP_394395 493 56346 N229 D F K V S V E N E H V L P F P
Nematode Worm Caenorhab. elegans NP_490958 465 51501 R198 E G V R I P K R D H F F Y Y P
Sea Urchin Strong. purpuratus XP_792601 513 57508 R121 K R E T K P G R L R G G V E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.7 96.6 84.9 N.A. 85.9 83.5 N.A. 38.5 61.1 59.3 35.1 N.A. 32.5 32.4 31.3 35.4
Protein Similarity: 100 45.9 98.4 91.4 N.A. 91.9 90.6 N.A. 47.9 74.5 72.6 54.1 N.A. 48.3 47.6 46.8 49.3
P-Site Identity: 100 100 100 46.6 N.A. 26.6 20 N.A. 0 0 20 13.3 N.A. 13.3 0 6.6 0
P-Site Similarity: 100 100 100 53.3 N.A. 26.6 20 N.A. 0 6.6 40 26.6 N.A. 20 20 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 36 29 0 0 0 29 0 0 29 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 22 0 0 22 0 % C
% Asp: 15 0 0 0 0 8 0 0 8 15 0 0 0 0 8 % D
% Glu: 8 8 8 0 0 0 22 0 15 0 0 0 0 15 0 % E
% Phe: 0 15 0 0 0 0 0 0 0 0 8 22 0 8 0 % F
% Gly: 22 50 8 0 8 8 8 0 0 0 8 15 0 0 8 % G
% His: 8 0 0 0 0 0 0 0 0 15 0 0 8 8 0 % H
% Ile: 0 0 0 0 8 8 8 0 0 0 0 0 8 0 0 % I
% Lys: 8 0 8 0 8 0 8 0 0 8 0 0 0 0 0 % K
% Leu: 0 0 15 8 0 0 8 0 36 8 0 8 15 0 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 15 0 0 0 0 0 15 8 % N
% Pro: 0 0 8 0 15 15 36 22 22 8 0 0 22 0 29 % P
% Gln: 0 0 43 0 8 0 0 0 8 8 0 0 0 0 0 % Q
% Arg: 0 8 0 8 0 0 0 22 8 8 0 0 0 0 0 % R
% Ser: 29 8 0 36 8 0 0 36 0 0 43 29 0 8 29 % S
% Thr: 0 0 0 29 8 22 8 0 0 0 8 0 0 0 0 % T
% Val: 0 0 8 15 0 8 0 0 0 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 22 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 22 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _