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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSUN4 All Species: 22.73
Human Site: S104 Identified Species: 38.46
UniProt: Q96CB9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CB9 NP_950245.2 384 43089 S104 D F V N E A I S H W E L Q S E
Chimpanzee Pan troglodytes XP_513142 833 91470 S104 D F V N E A I S H W E L Q S E
Rhesus Macaque Macaca mulatta XP_001108301 384 43099 S104 D F V N E A I S H W E L Q S E
Dog Lupus familis XP_853047 384 43059 S104 D F V S E A I S H G E P E P E
Cat Felis silvestris
Mouse Mus musculus Q9CZ57 381 42835 S104 D F V S E A I S H Q K L E P E
Rat Rattus norvegicus NP_001100148 381 42594 S104 D F V S E A I S Y Q K L E P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518738 248 26969
Chicken Gallus gallus XP_422449 404 44758 R106 D F V S E A A R R A R C W Q E
Frog Xenopus laevis Q5M7E3 406 46042 N126 V F T E V P L N L V G E K N D
Zebra Danio Brachydanio rerio Q4KMK0 367 41244 L104 E L G Y T N L L Q Q T H P E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608573 503 57519 Y221 W V A E S E H Y K Y Y Q T S A
Honey Bee Apis mellifera XP_394395 493 56346 Y214 W V L E S D H Y K F Y T K A D
Nematode Worm Caenorhab. elegans NP_490958 465 51501 V183 Q S N Q N K N V E I T G F E G
Sea Urchin Strong. purpuratus XP_792601 513 57508 G106 D F V Q L H A G D V K R L R I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.7 96.6 84.9 N.A. 85.9 83.5 N.A. 38.5 61.1 59.3 35.1 N.A. 32.5 32.4 31.3 35.4
Protein Similarity: 100 45.9 98.4 91.4 N.A. 91.9 90.6 N.A. 47.9 74.5 72.6 54.1 N.A. 48.3 47.6 46.8 49.3
P-Site Identity: 100 100 100 66.6 N.A. 66.6 60 N.A. 0 40 6.6 0 N.A. 6.6 0 0 20
P-Site Similarity: 100 100 100 80 N.A. 86.6 86.6 N.A. 0 46.6 40 13.3 N.A. 13.3 33.3 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 50 15 0 0 8 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 58 0 0 0 0 8 0 0 8 0 0 0 0 0 15 % D
% Glu: 8 0 0 22 50 8 0 0 8 0 29 8 22 15 50 % E
% Phe: 0 65 0 0 0 0 0 0 0 8 0 0 8 0 0 % F
% Gly: 0 0 8 0 0 0 0 8 0 8 8 8 0 0 8 % G
% His: 0 0 0 0 0 8 15 0 36 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 43 0 0 8 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 8 0 0 15 0 22 0 15 0 0 % K
% Leu: 0 8 8 0 8 0 15 8 8 0 0 36 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 22 8 8 8 8 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 0 8 8 22 0 % P
% Gln: 8 0 0 15 0 0 0 0 8 22 0 8 22 8 0 % Q
% Arg: 0 0 0 0 0 0 0 8 8 0 8 8 0 8 0 % R
% Ser: 0 8 0 29 15 0 0 43 0 0 0 0 0 29 8 % S
% Thr: 0 0 8 0 8 0 0 0 0 0 15 8 8 0 0 % T
% Val: 8 15 58 0 8 0 0 8 0 15 0 0 0 0 0 % V
% Trp: 15 0 0 0 0 0 0 0 0 22 0 0 8 0 0 % W
% Tyr: 0 0 0 8 0 0 0 15 8 8 15 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _