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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ROPN1L
All Species:
1.52
Human Site:
S221
Identified Species:
3.03
UniProt:
Q96C74
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96C74
NP_114122.2
230
26107
S221
P
K
R
K
L
L
E
S
I
E
N
S
E
D
V
Chimpanzee
Pan troglodytes
XP_517631
230
26090
N221
P
K
R
K
L
L
E
N
I
E
N
S
E
D
V
Rhesus Macaque
Macaca mulatta
XP_001085948
198
22364
Y190
S
S
S
E
T
E
S
Y
L
A
S
L
K
E
N
Dog
Lupus familis
XP_535790
218
24681
G207
S
R
K
N
G
M
I
G
L
S
D
F
F
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ00
230
25923
L221
E
K
D
N
I
E
S
L
E
E
K
A
L
E
A
Rat
Rattus norvegicus
Q4KLL5
212
23942
V200
G
P
D
G
L
I
K
V
N
D
F
T
Q
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519179
218
24250
G207
L
K
K
D
G
L
I
G
V
S
D
F
L
I
S
Chicken
Gallus gallus
XP_419011
218
24423
N209
S
G
M
V
L
L
R
N
F
Q
S
Q
P
S
T
Frog
Xenopus laevis
Q4V7T8
219
24389
F210
G
L
I
Q
P
R
N
F
L
S
S
Q
C
P
L
Zebra Danio
Brachydanio rerio
Q66IC9
218
24152
P207
S
Q
G
G
M
V
Q
P
S
N
F
T
S
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121035
280
31690
G257
E
C
A
K
V
Q
E
G
M
V
G
P
R
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793854
224
25048
A207
H
V
D
K
Q
N
G
A
V
Q
P
R
N
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
82.6
79.5
N.A.
76
38.2
N.A.
68.2
56.5
57.3
53.4
N.A.
N.A.
20.7
N.A.
50.4
Protein Similarity:
100
99.5
84.7
89.1
N.A.
87.8
58.7
N.A.
82.6
76
75.2
67.3
N.A.
N.A.
37.5
N.A.
70
P-Site Identity:
100
93.3
0
0
N.A.
13.3
6.6
N.A.
13.3
13.3
0
0
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
33.3
40
N.A.
33.3
46.6
N.A.
33.3
33.3
26.6
33.3
N.A.
N.A.
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
9
0
9
0
9
0
0
9
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
25
9
0
0
0
0
0
9
17
0
0
17
0
% D
% Glu:
17
0
0
9
0
17
25
0
9
25
0
0
17
17
0
% E
% Phe:
0
0
0
0
0
0
0
9
9
0
17
17
9
9
0
% F
% Gly:
17
9
9
17
17
0
9
25
0
0
9
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
9
0
9
9
17
0
17
0
0
0
0
9
0
% I
% Lys:
0
34
17
34
0
0
9
0
0
0
9
0
9
0
0
% K
% Leu:
9
9
0
0
34
34
0
9
25
0
0
9
17
9
34
% L
% Met:
0
0
9
0
9
9
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
0
9
9
17
9
9
17
0
9
17
9
% N
% Pro:
17
9
0
0
9
0
0
9
0
0
9
9
9
9
9
% P
% Gln:
0
9
0
9
9
9
9
0
0
17
0
17
9
0
0
% Q
% Arg:
0
9
17
0
0
9
9
0
0
0
0
9
9
0
0
% R
% Ser:
34
9
9
0
0
0
17
9
9
25
25
17
9
9
9
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
0
17
0
0
9
% T
% Val:
0
9
0
9
9
9
0
9
17
9
0
0
0
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _