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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPWD1
All Species:
35.15
Human Site:
Y257
Identified Species:
59.49
UniProt:
Q96BP3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BP3
NP_056157.1
646
73575
Y257
W
T
G
P
P
H
E
Y
K
F
P
K
N
V
N
Chimpanzee
Pan troglodytes
XP_001164190
646
73612
Y257
W
T
G
P
P
H
E
Y
K
F
P
K
N
V
N
Rhesus Macaque
Macaca mulatta
XP_001085845
646
73558
Y257
W
T
G
P
P
H
E
Y
K
F
P
K
N
V
N
Dog
Lupus familis
XP_535256
646
73593
Y257
W
T
G
P
P
H
E
Y
K
F
P
K
N
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEC6
646
73412
Y257
W
T
G
P
P
H
E
Y
K
F
P
K
N
V
N
Rat
Rattus norvegicus
NP_001099876
646
73476
Y257
W
T
G
P
P
H
E
Y
K
F
P
K
T
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424751
625
70981
Y236
W
T
G
T
P
H
E
Y
K
F
P
K
N
V
N
Frog
Xenopus laevis
NP_001091218
642
72464
Y253
W
T
G
P
P
R
G
Y
K
F
P
N
N
V
H
Zebra Danio
Brachydanio rerio
NP_001092228
622
70606
F233
W
T
G
L
P
S
E
F
K
F
P
R
Q
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611935
637
71743
K249
Q
N
S
K
Y
D
Y
K
F
P
Q
R
L
V
N
Honey Bee
Apis mellifera
XP_396986
612
69983
S234
P
K
C
V
T
F
E
S
K
L
D
T
D
L
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177287
619
70117
Y231
W
M
G
P
K
K
D
Y
R
Y
P
S
C
V
S
Poplar Tree
Populus trichocarpa
XP_002312902
620
69816
S250
E
I
V
K
C
K
T
S
V
S
T
M
E
V
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190046
631
70965
Q236
Y
W
S
A
T
T
L
Q
F
P
E
D
E
V
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.3
97.2
N.A.
96.4
96.5
N.A.
N.A.
89.3
84.3
81.5
N.A.
58.6
63.6
N.A.
63.7
Protein Similarity:
100
100
99.8
98.6
N.A.
97.9
97.9
N.A.
N.A.
93
90.4
89.3
N.A.
76.6
77.7
N.A.
78.9
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
93.3
73.3
60
N.A.
13.3
13.3
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
93.3
80
80
N.A.
20
26.6
N.A.
66.6
Percent
Protein Identity:
50.1
N.A.
N.A.
50.9
N.A.
N.A.
Protein Similarity:
68.4
N.A.
N.A.
69.2
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
8
8
0
0
0
8
8
8
0
8
% D
% Glu:
8
0
0
0
0
0
65
0
0
0
8
0
15
0
0
% E
% Phe:
0
0
0
0
0
8
0
8
15
65
0
0
0
0
8
% F
% Gly:
0
0
72
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
15
8
15
0
8
72
0
0
50
0
0
0
% K
% Leu:
0
0
0
8
0
0
8
0
0
8
0
0
8
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
8
50
0
65
% N
% Pro:
8
0
0
58
65
0
0
0
0
15
72
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
8
0
0
8
0
8
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
8
0
0
15
0
0
0
% R
% Ser:
0
0
15
0
0
8
0
15
0
8
0
8
0
0
15
% S
% Thr:
0
65
0
8
15
8
8
0
0
0
8
8
8
0
0
% T
% Val:
0
0
8
8
0
0
0
0
8
0
0
0
0
93
0
% V
% Trp:
72
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
8
65
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _