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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPWD1
All Species:
37.58
Human Site:
T227
Identified Species:
63.59
UniProt:
Q96BP3
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BP3
NP_056157.1
646
73575
T227
K
L
H
T
S
P
L
T
Q
I
R
L
N
P
V
Chimpanzee
Pan troglodytes
XP_001164190
646
73612
T227
K
L
H
T
S
P
L
T
Q
I
R
L
N
P
V
Rhesus Macaque
Macaca mulatta
XP_001085845
646
73558
T227
K
L
H
T
S
P
L
T
Q
I
R
L
N
P
V
Dog
Lupus familis
XP_535256
646
73593
T227
K
L
H
T
S
P
L
T
Q
I
R
L
N
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEC6
646
73412
T227
K
L
H
V
S
P
L
T
Q
I
R
L
N
P
V
Rat
Rattus norvegicus
NP_001099876
646
73476
T227
K
L
H
V
S
P
L
T
Q
I
R
L
N
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424751
625
70981
T206
K
L
H
T
S
S
L
T
Q
I
R
L
N
P
V
Frog
Xenopus laevis
NP_001091218
642
72464
T223
K
L
H
S
S
P
L
T
T
I
R
L
N
P
V
Zebra Danio
Brachydanio rerio
NP_001092228
622
70606
S203
K
M
H
T
T
P
L
S
Q
I
R
L
N
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611935
637
71743
A219
L
H
S
A
P
V
V
A
M
C
L
N
V
A
M
Honey Bee
Apis mellifera
XP_396986
612
69983
T204
K
Y
N
S
I
Y
E
T
C
I
S
V
D
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177287
619
70117
I201
K
K
H
S
A
P
V
I
L
I
K
Y
N
P
V
Poplar Tree
Populus trichocarpa
XP_002312902
620
69816
S220
K
G
L
I
E
Y
W
S
P
T
T
L
K
F
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190046
631
70965
I206
K
E
I
H
M
N
P
I
K
V
M
K
Y
N
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.3
97.2
N.A.
96.4
96.5
N.A.
N.A.
89.3
84.3
81.5
N.A.
58.6
63.6
N.A.
63.7
Protein Similarity:
100
100
99.8
98.6
N.A.
97.9
97.9
N.A.
N.A.
93
90.4
89.3
N.A.
76.6
77.7
N.A.
78.9
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
86.6
73.3
N.A.
0
20
N.A.
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
13.3
46.6
N.A.
73.3
Percent
Protein Identity:
50.1
N.A.
N.A.
50.9
N.A.
N.A.
Protein Similarity:
68.4
N.A.
N.A.
69.2
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
8
0
0
0
0
0
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
8
0
0
8
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
72
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
8
0
0
15
0
79
0
0
0
0
0
% I
% Lys:
93
8
0
0
0
0
0
0
8
0
8
8
8
8
8
% K
% Leu:
8
58
8
0
0
0
65
0
8
0
8
72
0
0
0
% L
% Met:
0
8
0
0
8
0
0
0
8
0
8
0
0
0
8
% M
% Asn:
0
0
8
0
0
8
0
0
0
0
0
8
72
8
0
% N
% Pro:
0
0
0
0
8
65
8
0
8
0
0
0
0
65
15
% P
% Gln:
0
0
0
0
0
0
0
0
58
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
65
0
0
0
0
% R
% Ser:
0
0
8
22
58
8
0
15
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
43
8
0
0
65
8
8
8
0
0
0
0
% T
% Val:
0
0
0
15
0
8
15
0
0
8
0
8
8
0
65
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
15
0
0
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _