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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPWD1 All Species: 44.85
Human Site: S289 Identified Species: 75.9
UniProt: Q96BP3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BP3 NP_056157.1 646 73575 S289 Y P T S V C F S P D G K K I A
Chimpanzee Pan troglodytes XP_001164190 646 73612 S289 Y P T S I C F S P D G K K I A
Rhesus Macaque Macaca mulatta XP_001085845 646 73558 S289 Y P T S I C F S P D G K K I A
Dog Lupus familis XP_535256 646 73593 S289 Y P T S I C F S P D G K K I A
Cat Felis silvestris
Mouse Mus musculus Q8CEC6 646 73412 S289 Y P T S I C F S P D G K K I A
Rat Rattus norvegicus NP_001099876 646 73476 S289 Y P T S I C F S P D G K K I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424751 625 70981 S268 Y P S S I S F S P D G K K M A
Frog Xenopus laevis NP_001091218 642 72464 S285 C L T S I S F S P D G K K M A
Zebra Danio Brachydanio rerio NP_001092228 622 70606 S265 Y P T S L A F S Q D G K K M A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611935 637 71743 T281 Q V T G L A A T P D G K R F A
Honey Bee Apis mellifera XP_396986 612 69983 S266 G K R F A S L S G D R K V R V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177287 619 70117 S263 V P T S L S F S P D G Q L I A
Poplar Tree Populus trichocarpa XP_002312902 620 69816 L282 F W F R T G K L R R V Y D E S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_190046 631 70965 S268 T I S A I E V S P D G K Q F S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.3 97.2 N.A. 96.4 96.5 N.A. N.A. 89.3 84.3 81.5 N.A. 58.6 63.6 N.A. 63.7
Protein Similarity: 100 100 99.8 98.6 N.A. 97.9 97.9 N.A. N.A. 93 90.4 89.3 N.A. 76.6 77.7 N.A. 78.9
P-Site Identity: 100 93.3 93.3 93.3 N.A. 93.3 93.3 N.A. N.A. 73.3 66.6 73.3 N.A. 40 20 N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 80 86.6 N.A. 60 20 N.A. 80
Percent
Protein Identity: 50.1 N.A. N.A. 50.9 N.A. N.A.
Protein Similarity: 68.4 N.A. N.A. 69.2 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 15 8 0 0 0 0 0 0 0 79 % A
% Cys: 8 0 0 0 0 43 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 93 0 0 8 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % E
% Phe: 8 0 8 8 0 0 72 0 0 0 0 0 0 15 0 % F
% Gly: 8 0 0 8 0 8 0 0 8 0 86 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 58 0 0 0 0 0 0 0 0 50 0 % I
% Lys: 0 8 0 0 0 0 8 0 0 0 0 86 65 0 0 % K
% Leu: 0 8 0 0 22 0 8 8 0 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 22 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 65 0 0 0 0 0 0 79 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 8 0 0 8 8 0 0 % Q
% Arg: 0 0 8 8 0 0 0 0 8 8 8 0 8 8 0 % R
% Ser: 0 0 15 72 0 29 0 86 0 0 0 0 0 0 15 % S
% Thr: 8 0 72 0 8 0 0 8 0 0 0 0 0 0 0 % T
% Val: 8 8 0 0 8 0 8 0 0 0 8 0 8 0 8 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 58 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _