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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PINX1 All Species: 38.18
Human Site: S139 Identified Species: 70
UniProt: Q96BK5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BK5 NP_060354.4 328 37035 S139 G K D L S S R S K T D L D C I
Chimpanzee Pan troglodytes XP_519603 333 37605 S139 G K D L S S R S K T D L D C I
Rhesus Macaque Macaca mulatta XP_001089816 328 36769 S139 G K D L S S R S K T D L D C I
Dog Lupus familis XP_849859 314 35718 S139 G K D L S C R S K T D L D C I
Cat Felis silvestris
Mouse Mus musculus Q9CZX5 332 37202 S139 G K D L S S R S E T D L D C I
Rat Rattus norvegicus A4L691 331 36692 S139 G K D L S S R S E T D L D C I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420036 356 40488 S139 G K D L S L R S E D D L S C I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001013283 355 40546 S137 G K D L S S R S E T D L A C I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611495 726 82612 S163 G K D L A L Y S E K D L A N I
Honey Bee Apis mellifera XP_391986 378 43625 S140 G K D V N K Y S A K D L A N I
Nematode Worm Caenorhab. elegans NP_495955 339 39018 S143 A K D T S N Y S D S H K K G I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53335 271 31293 N99 Q R I L G R L N G K E S K I S
Red Bread Mold Neurospora crassa Q7SHT5 369 41722 V140 G G W L V G D V V K E K V T E
Conservation
Percent
Protein Identity: 100 96.6 94.2 75.9 N.A. 72.8 69.4 N.A. N.A. 48.5 N.A. 48.7 N.A. 22.7 32 28.9 N.A.
Protein Similarity: 100 97.5 96 82.6 N.A. 81 79.1 N.A. N.A. 64 N.A. 64.2 N.A. 31.5 48.4 47.4 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 73.3 N.A. 86.6 N.A. 53.3 46.6 33.3 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 80 N.A. 93.3 N.A. 66.6 60 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.6 23.5
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 40.6
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 0 0 8 0 0 0 24 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 62 0 % C
% Asp: 0 0 85 0 0 0 8 0 8 8 77 0 47 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 39 0 16 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 85 8 0 0 8 8 0 0 8 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 85 % I
% Lys: 0 85 0 0 0 8 0 0 31 31 0 16 16 0 0 % K
% Leu: 0 0 0 85 0 16 8 0 0 0 0 77 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 8 0 8 0 0 0 0 0 16 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 8 62 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 70 47 0 85 0 8 0 8 8 0 8 % S
% Thr: 0 0 0 8 0 0 0 0 0 54 0 0 0 8 0 % T
% Val: 0 0 0 8 8 0 0 8 8 0 0 0 8 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 24 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _