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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3KBP1
All Species:
18.79
Human Site:
S447
Identified Species:
45.93
UniProt:
Q96B97
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B97
NP_001019837.1
665
73126
S447
D
L
A
G
S
S
L
S
G
I
L
D
K
D
L
Chimpanzee
Pan troglodytes
XP_520965
672
73799
D454
C
P
G
I
A
F
E
D
R
Q
L
D
D
G
H
Rhesus Macaque
Macaca mulatta
XP_001085866
626
68239
S410
D
L
A
G
S
S
L
S
G
I
L
D
K
D
L
Dog
Lupus familis
XP_849391
628
68475
S409
D
L
V
G
S
S
I
S
G
I
L
D
K
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R550
709
78152
S491
D
L
A
G
S
A
L
S
G
I
L
D
K
D
L
Rat
Rattus norvegicus
Q925Q9
709
78067
S491
D
L
A
G
S
T
L
S
G
I
L
D
K
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514038
690
76640
A474
I
E
L
G
I
T
L
A
S
P
P
D
K
D
L
Chicken
Gallus gallus
Q5ZLR6
764
85889
E499
G
M
T
L
T
K
L
E
D
A
E
G
N
E
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666707
602
66567
P385
P
P
K
R
P
D
R
P
E
R
P
A
V
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195816
853
91426
S630
H
D
P
P
S
T
P
S
N
T
S
S
S
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
90.3
89.3
N.A.
88.2
87.7
N.A.
80.5
20
N.A.
48.2
N.A.
N.A.
N.A.
N.A.
30
Protein Similarity:
100
92.8
90.9
91.2
N.A.
91.1
90.4
N.A.
87.5
36.2
N.A.
65.1
N.A.
N.A.
N.A.
N.A.
45.7
P-Site Identity:
100
13.3
100
86.6
N.A.
93.3
93.3
N.A.
40
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
20
100
93.3
N.A.
100
100
N.A.
53.3
26.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
40
0
10
10
0
10
0
10
0
10
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
10
0
0
0
10
0
10
10
0
0
70
10
60
0
% D
% Glu:
0
10
0
0
0
0
10
10
10
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
60
0
0
0
0
50
0
0
10
0
10
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% H
% Ile:
10
0
0
10
10
0
10
0
0
50
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
10
0
0
0
0
0
0
60
0
0
% K
% Leu:
0
50
10
10
0
0
60
0
0
0
60
0
0
0
60
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
10
% N
% Pro:
10
20
10
10
10
0
10
10
0
10
20
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
10
0
10
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
60
30
0
60
10
0
10
10
10
0
10
% S
% Thr:
0
0
10
0
10
30
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _