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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS33A
All Species:
23.94
Human Site:
T106
Identified Species:
35.11
UniProt:
Q96AX1
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AX1
NP_075067.2
596
67611
T106
S
E
D
R
R
G
P
T
R
D
F
H
I
L
F
Chimpanzee
Pan troglodytes
XP_001167547
566
64240
T76
S
E
D
R
R
G
P
T
R
D
F
H
I
L
F
Rhesus Macaque
Macaca mulatta
XP_001098488
534
60475
R75
V
L
G
S
F
I
H
R
E
E
Y
S
L
D
L
Dog
Lupus familis
XP_534660
596
67606
T106
S
E
D
R
R
G
P
T
R
D
F
H
I
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2N9
598
67522
T106
S
E
D
R
R
G
P
T
R
D
F
H
I
L
F
Rat
Rattus norvegicus
Q63615
597
67495
T106
S
E
D
R
R
G
P
T
R
D
F
H
I
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506548
578
65937
T88
S
E
D
R
R
S
P
T
R
D
F
H
I
L
F
Chicken
Gallus gallus
XP_415153
601
68528
Q107
E
D
R
G
R
S
P
Q
R
D
F
H
I
L
F
Frog
Xenopus laevis
NP_001121352
601
68172
Q107
E
E
R
G
R
F
P
Q
R
D
F
Y
I
L
F
Zebra Danio
Brachydanio rerio
NP_001093443
599
68084
P105
S
S
E
D
K
L
Q
P
R
E
F
H
I
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y1I2
617
68748
G107
A
G
G
R
A
A
A
G
R
Q
Y
H
I
L
F
Honey Bee
Apis mellifera
XP_395353
609
68702
R108
G
E
E
G
K
R
P
R
K
E
F
H
L
F
F
Nematode Worm
Caenorhab. elegans
P34260
603
68147
Y118
R
N
D
S
K
I
L
Y
Q
V
F
F
I
P
E
Sea Urchin
Strong. purpuratus
XP_798265
622
70760
R116
E
E
N
P
G
R
F
R
K
E
F
H
I
Y
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94KJ7
592
66894
I105
Q
N
D
I
A
K
A
I
Q
R
D
Y
Y
V
Y
Baker's Yeast
Sacchar. cerevisiae
P20795
691
79253
Q80
S
A
L
G
S
V
P
Q
M
D
L
I
F
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
89.5
98.3
N.A.
97.3
96.8
N.A.
90.5
91
85.6
83.9
N.A.
44.4
52.5
27.6
63.3
Protein Similarity:
100
94.8
89.5
99.6
N.A.
98.8
98.9
N.A.
94.3
94.6
91.6
91.4
N.A.
61.9
71.2
49
79.4
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
93.3
60
60
46.6
N.A.
40
33.3
20
33.3
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
93.3
66.6
66.6
66.6
N.A.
53.3
66.6
33.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.5
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
13
7
13
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
50
7
0
0
0
0
0
57
7
0
0
7
0
% D
% Glu:
19
57
13
0
0
0
0
0
7
25
0
0
0
0
7
% E
% Phe:
0
0
0
0
7
7
7
0
0
0
75
7
7
7
75
% F
% Gly:
7
7
13
25
7
32
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
69
0
0
0
% H
% Ile:
0
0
0
7
0
13
0
7
0
0
0
7
75
0
7
% I
% Lys:
0
0
0
0
19
7
0
0
13
0
0
0
0
0
0
% K
% Leu:
0
7
7
0
0
7
7
0
0
0
7
0
13
69
7
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
13
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
63
7
0
0
0
0
0
7
0
% P
% Gln:
7
0
0
0
0
0
7
19
13
7
0
0
0
0
0
% Q
% Arg:
7
0
13
44
50
13
0
19
63
7
0
0
0
0
0
% R
% Ser:
50
7
0
13
7
13
0
0
0
0
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
38
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
0
7
0
0
0
7
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
13
13
7
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _