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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS33A
All Species:
43.64
Human Site:
S133
Identified Species:
64
UniProt:
Q96AX1
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AX1
NP_075067.2
596
67611
S133
K
D
L
G
V
L
G
S
F
I
H
R
E
E
Y
Chimpanzee
Pan troglodytes
XP_001167547
566
64240
S103
K
D
L
G
V
L
G
S
F
I
H
R
E
E
Y
Rhesus Macaque
Macaca mulatta
XP_001098488
534
60475
Y102
E
G
A
F
K
E
C
Y
L
E
G
D
Q
T
S
Dog
Lupus familis
XP_534660
596
67606
S133
K
D
L
G
V
L
G
S
F
I
H
R
E
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2N9
598
67522
S133
K
D
V
G
V
L
G
S
F
I
H
R
E
E
Y
Rat
Rattus norvegicus
Q63615
597
67495
S133
K
D
L
G
V
L
G
S
F
I
Y
R
E
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506548
578
65937
S115
K
D
Q
G
V
L
G
S
F
I
H
R
E
E
Y
Chicken
Gallus gallus
XP_415153
601
68528
S134
K
E
Q
G
V
L
G
S
F
I
H
R
E
Q
Y
Frog
Xenopus laevis
NP_001121352
601
68172
S134
K
D
L
G
V
L
G
S
F
M
H
R
D
E
Y
Zebra Danio
Brachydanio rerio
NP_001093443
599
68084
S132
K
E
K
G
V
L
N
S
F
T
N
I
D
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y1I2
617
68748
S134
E
V
S
G
V
L
G
S
F
G
N
I
E
E
L
Honey Bee
Apis mellifera
XP_395353
609
68702
S135
Q
N
R
G
V
F
G
S
F
T
L
I
E
E
F
Nematode Worm
Caenorhab. elegans
P34260
603
68147
R145
A
E
G
K
Y
W
E
R
L
E
S
V
K
E
I
Sea Urchin
Strong. purpuratus
XP_798265
622
70760
T143
T
E
L
G
V
Y
G
T
L
N
T
V
G
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94KJ7
592
66894
N132
L
E
Q
E
K
V
H
N
L
V
T
V
K
E
F
Baker's Yeast
Sacchar. cerevisiae
P20795
691
79253
N107
L
D
A
A
Q
K
H
N
L
S
S
L
H
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
89.5
98.3
N.A.
97.3
96.8
N.A.
90.5
91
85.6
83.9
N.A.
44.4
52.5
27.6
63.3
Protein Similarity:
100
94.8
89.5
99.6
N.A.
98.8
98.9
N.A.
94.3
94.6
91.6
91.4
N.A.
61.9
71.2
49
79.4
P-Site Identity:
100
100
0
100
N.A.
93.3
93.3
N.A.
93.3
80
86.6
53.3
N.A.
53.3
46.6
6.6
40
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
93.3
93.3
100
73.3
N.A.
66.6
66.6
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.5
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
13
7
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
50
0
0
0
0
0
0
0
0
0
7
13
0
0
% D
% Glu:
13
32
0
7
0
7
7
0
0
13
0
0
57
82
0
% E
% Phe:
0
0
0
7
0
7
0
0
69
0
0
0
0
0
13
% F
% Gly:
0
7
7
75
0
0
69
0
0
7
7
0
7
0
0
% G
% His:
0
0
0
0
0
0
13
0
0
0
44
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
44
0
19
0
7
13
% I
% Lys:
57
0
7
7
13
7
0
0
0
0
0
0
13
0
0
% K
% Leu:
13
0
38
0
0
63
0
0
32
0
7
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
7
13
0
7
13
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
19
0
7
0
0
0
0
0
0
0
7
7
0
% Q
% Arg:
0
0
7
0
0
0
0
7
0
0
0
50
0
0
0
% R
% Ser:
0
0
7
0
0
0
0
69
0
7
13
0
0
0
7
% S
% Thr:
7
0
0
0
0
0
0
7
0
13
13
0
0
7
0
% T
% Val:
0
7
7
0
75
7
0
0
0
7
0
19
0
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
7
0
7
0
0
7
0
0
0
63
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _