KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F7
All Species:
9.39
Human Site:
S591
Identified Species:
22.96
UniProt:
Q96AV8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AV8
NP_976328
911
99845
S591
V
E
L
S
S
A
P
S
A
Q
K
R
L
C
E
Chimpanzee
Pan troglodytes
XP_001161983
911
99876
S591
V
E
L
S
S
A
P
S
A
Q
K
R
L
C
E
Rhesus Macaque
Macaca mulatta
XP_001083107
910
99890
S591
V
E
L
S
S
A
P
S
A
Q
K
R
L
S
E
Dog
Lupus familis
XP_539692
955
104248
R634
Q
K
R
L
G
E
E
R
K
P
Q
A
E
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6S7F2
904
99516
E591
S
A
Q
K
R
L
C
E
E
R
D
P
Q
E
E
Rat
Rattus norvegicus
NP_001101562
514
58347
V203
S
L
H
L
V
S
R
V
A
K
N
Q
Y
G
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505920
640
67606
C329
A
G
S
P
K
R
G
C
R
A
C
A
S
L
E
Chicken
Gallus gallus
XP_416110
975
105252
K648
V
P
P
A
N
C
Q
K
R
S
S
H
R
C
T
Frog
Xenopus laevis
NP_001090423
867
95474
S555
N
L
S
E
G
K
A
S
E
Q
L
A
K
S
L
Zebra Danio
Brachydanio rerio
NP_001038612
723
79307
V412
R
Y
S
T
D
E
P
V
D
Y
S
R
K
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.2
78.2
N.A.
79
49.5
N.A.
39.8
51.6
45.9
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.1
82.9
N.A.
85.7
53.5
N.A.
49.5
64.5
62.7
50.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
6.6
6.6
N.A.
6.6
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
13.3
N.A.
13.3
26.6
N.A.
6.6
26.6
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
0
30
10
0
40
10
0
30
0
0
0
% A
% Cys:
0
0
0
0
0
10
10
10
0
0
10
0
0
30
0
% C
% Asp:
0
0
0
0
10
0
0
0
10
0
10
0
0
0
0
% D
% Glu:
0
30
0
10
0
20
10
10
20
0
0
0
10
20
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
20
0
10
0
0
0
0
0
0
10
10
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
10
10
10
0
10
10
10
30
0
20
0
0
% K
% Leu:
0
20
30
20
0
10
0
0
0
0
10
0
30
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
10
10
10
0
0
40
0
0
10
0
10
0
0
10
% P
% Gln:
10
0
10
0
0
0
10
0
0
40
10
10
10
0
0
% Q
% Arg:
10
0
10
0
10
10
10
10
20
10
0
40
10
0
0
% R
% Ser:
20
0
30
30
30
10
0
40
0
10
20
0
10
30
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
40
0
0
0
10
0
0
20
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
10
0
0
0
0
0
0
0
10
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _