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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB7B
All Species:
39.09
Human Site:
Y149
Identified Species:
57.33
UniProt:
Q96AH8
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AH8
NP_001157994.1
199
22511
Y149
C
R
E
K
D
I
P
Y
F
E
V
S
A
K
N
Chimpanzee
Pan troglodytes
XP_528612
183
20423
Q135
L
A
D
R
K
V
P
Q
E
V
A
Q
G
W
C
Rhesus Macaque
Macaca mulatta
XP_001082547
189
21247
E136
A
D
R
K
V
P
Q
E
V
A
Q
G
W
C
R
Dog
Lupus familis
XP_848668
200
22608
Y149
C
K
E
K
D
I
P
Y
F
E
V
S
A
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEA8
199
22483
Y149
C
K
E
K
D
M
P
Y
F
E
V
S
A
K
N
Rat
Rattus norvegicus
P09527
207
23485
Y151
Y
S
K
N
N
I
P
Y
F
E
T
S
A
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509956
200
22531
Y149
C
T
E
K
D
I
P
Y
F
E
V
S
A
K
N
Chicken
Gallus gallus
XP_001235016
253
27912
Y156
C
K
E
K
D
I
P
Y
F
E
V
S
A
K
N
Frog
Xenopus laevis
NP_001085745
201
22757
Y149
C
K
G
K
N
L
S
Y
L
E
V
S
A
K
N
Zebra Danio
Brachydanio rerio
NP_957222
207
23534
Y151
Q
S
K
N
N
I
P
Y
F
E
T
S
A
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120025
207
23218
Y151
Q
S
K
N
N
I
P
Y
F
E
T
S
A
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001116983
205
23050
Y151
D
S
K
N
S
I
P
Y
F
E
T
S
A
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q05737
203
22457
F147
A
D
E
M
G
I
P
F
M
E
T
S
A
K
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04157
203
22926
Y154
A
E
K
G
N
I
V
Y
F
E
T
S
A
K
E
Baker's Yeast
Sacchar. cerevisiae
P32939
208
23024
L154
K
S
L
G
D
I
P
L
F
L
T
S
A
K
N
Red Bread Mold
Neurospora crassa
Q9C2L8
205
23110
Y153
Q
S
K
G
N
I
P
Y
F
E
T
S
A
K
E
Conservation
Percent
Protein Identity:
100
88.4
90.4
93
N.A.
88.4
47.3
N.A.
78.5
55.7
62.1
48.3
N.A.
N.A.
45.8
N.A.
46.3
Protein Similarity:
100
89.9
91.9
97.5
N.A.
92.9
67.1
N.A.
90
67.1
74.6
67.6
N.A.
N.A.
66.1
N.A.
65.3
P-Site Identity:
100
6.6
6.6
93.3
N.A.
86.6
53.3
N.A.
93.3
93.3
60
53.3
N.A.
N.A.
53.3
N.A.
53.3
P-Site Similarity:
100
26.6
6.6
100
N.A.
100
66.6
N.A.
93.3
100
80
66.6
N.A.
N.A.
66.6
N.A.
60
Percent
Protein Identity:
N.A.
35.9
N.A.
41.8
42.3
43.4
Protein Similarity:
N.A.
55.1
N.A.
64
62.5
66.3
P-Site Identity:
N.A.
53.3
N.A.
46.6
53.3
53.3
P-Site Similarity:
N.A.
60
N.A.
60
53.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
7
0
0
0
0
0
0
0
7
7
0
88
0
0
% A
% Cys:
38
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% C
% Asp:
7
13
7
0
38
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
38
0
0
0
0
7
7
82
0
0
0
0
38
% E
% Phe:
0
0
0
0
0
0
0
7
75
0
0
0
0
0
0
% F
% Gly:
0
0
7
19
7
0
0
0
0
0
0
7
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
25
38
44
7
0
0
0
0
0
0
0
0
88
0
% K
% Leu:
7
0
7
0
0
7
0
7
7
7
0
0
0
0
0
% L
% Met:
0
0
0
7
0
7
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
25
38
0
0
0
0
0
0
0
0
0
50
% N
% Pro:
0
0
0
0
0
7
82
0
0
0
0
0
0
0
0
% P
% Gln:
19
0
0
0
0
0
7
7
0
0
7
7
0
0
0
% Q
% Arg:
0
7
7
7
0
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
38
0
0
7
0
7
0
0
0
0
88
0
0
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
0
50
0
0
0
0
% T
% Val:
0
0
0
0
7
7
7
0
7
7
38
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% W
% Tyr:
7
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _