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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB7B
All Species:
0
Human Site:
S194
Identified Species:
0
UniProt:
Q96AH8
Number Species:
15
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AH8
NP_001157994.1
199
22511
S194
I
K
L
S
P
D
Q
S
R
S
R
C
C
_
_
Chimpanzee
Pan troglodytes
XP_528612
183
20423
Rhesus Macaque
Macaca mulatta
XP_001082547
189
21247
E180
S
R
P
S
L
S
R
E
R
E
S
S
E
V
S
Dog
Lupus familis
XP_848668
200
22608
Q194
I
K
L
S
P
E
D
Q
S
R
S
R
C
C
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEA8
199
22483
P194
I
K
L
S
P
G
Q
P
K
S
R
C
C
_
_
Rat
Rattus norvegicus
P09527
207
23485
E196
P
I
K
L
D
K
N
E
R
A
K
A
S
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509956
200
22531
Q194
I
K
L
T
P
E
D
Q
T
Q
S
K
C
C
_
Chicken
Gallus gallus
XP_001235016
253
27912
A201
D
V
V
F
L
I
P
A
L
I
T
L
L
I
P
Frog
Xenopus laevis
NP_001085745
201
22757
D194
I
K
L
Y
P
T
E
D
S
N
S
N
T
C
C
Zebra Danio
Brachydanio rerio
NP_957222
207
23534
D196
P
I
K
L
D
R
N
D
R
A
K
P
S
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120025
207
23218
Q196
Q
I
K
L
T
N
D
Q
R
N
N
G
K
S
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001116983
205
23050
N196
Q
I
K
L
D
N
D
N
K
G
K
T
E
G
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q05737
203
22457
Q196
I
R
G
Q
P
V
N
Q
K
T
S
C
C
S
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04157
203
22926
Baker's Yeast
Sacchar. cerevisiae
P32939
208
23024
L199
N
D
A
I
N
I
R
L
D
G
E
N
N
S
C
Red Bread Mold
Neurospora crassa
Q9C2L8
205
23110
N198
P
I
N
I
H
I
E
N
D
R
D
G
C
A
C
Conservation
Percent
Protein Identity:
100
88.4
90.4
93
N.A.
88.4
47.3
N.A.
78.5
55.7
62.1
48.3
N.A.
N.A.
45.8
N.A.
46.3
Protein Similarity:
100
89.9
91.9
97.5
N.A.
92.9
67.1
N.A.
90
67.1
74.6
67.6
N.A.
N.A.
66.1
N.A.
65.3
P-Site Identity:
100
0
13.3
42.8
N.A.
76.9
6.6
N.A.
35.7
0
26.6
6.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
0
26.6
50
N.A.
84.6
20
N.A.
50
20
40
20
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
N.A.
35.9
N.A.
41.8
42.3
43.4
Protein Similarity:
N.A.
55.1
N.A.
64
62.5
66.3
P-Site Identity:
N.A.
26.6
N.A.
0
0
6.6
P-Site Similarity:
N.A.
46.6
N.A.
0
6.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
7
0
13
0
7
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
19
38
19
25
% C
% Asp:
7
7
0
0
19
7
25
13
13
0
7
0
0
0
7
% D
% Glu:
0
0
0
0
0
13
13
13
0
7
7
0
13
0
13
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
7
0
0
0
13
0
13
0
7
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
38
32
0
13
0
19
0
0
0
7
0
0
0
7
0
% I
% Lys:
0
32
25
0
0
7
0
0
19
0
19
7
7
0
0
% K
% Leu:
0
0
32
25
13
0
0
7
7
0
0
7
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
7
13
19
13
0
13
7
13
7
0
0
% N
% Pro:
19
0
7
0
38
0
7
7
0
0
0
7
0
0
7
% P
% Gln:
13
0
0
7
0
0
13
25
0
7
0
0
0
0
0
% Q
% Arg:
0
13
0
0
0
7
13
0
32
13
13
7
0
0
0
% R
% Ser:
7
0
0
25
0
7
0
7
13
13
32
7
13
19
13
% S
% Thr:
0
0
0
7
7
7
0
0
7
7
7
7
7
0
0
% T
% Val:
0
7
7
0
0
7
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
25
% _