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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC59
All Species:
11.52
Human Site:
S229
Identified Species:
25.33
UniProt:
Q96AG4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AG4
NP_060979.2
307
34930
S229
N
Q
A
P
K
S
K
S
G
S
R
P
R
K
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093756
240
27274
E158
V
Q
A
D
Q
E
R
E
R
Q
R
R
L
E
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q922Q8
307
34859
S229
N
Q
A
P
K
S
K
S
G
S
R
P
R
K
P
Rat
Rattus norvegicus
Q5RJR8
307
34851
S229
N
Q
A
P
K
S
K
S
G
S
R
P
R
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510940
305
34466
P227
E
P
R
P
K
P
A
P
T
P
R
P
P
R
P
Chicken
Gallus gallus
Q5F334
339
38647
S262
V
Q
T
R
K
L
A
S
S
S
R
P
P
Q
P
Frog
Xenopus laevis
Q8AVS8
307
35413
N226
A
E
E
E
P
T
E
N
H
K
R
M
A
T
P
Zebra Danio
Brachydanio rerio
Q6NWG1
314
35886
A226
E
E
K
K
K
K
A
A
Q
N
Q
G
K
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121810
270
31077
N189
E
P
P
K
L
T
L
N
N
Q
I
N
K
E
Y
Nematode Worm
Caenorhab. elegans
NP_499730
444
49391
A189
Q
E
K
K
E
K
A
A
A
K
K
E
K
D
A
Sea Urchin
Strong. purpuratus
XP_793338
179
20031
D116
L
K
S
L
R
W
L
D
V
K
E
N
K
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
75.5
N.A.
N.A.
95.4
94.4
N.A.
74.9
65.1
57.6
55.4
N.A.
N.A.
32.2
27.7
33.2
Protein Similarity:
100
N.A.
76.5
N.A.
N.A.
97.7
96.4
N.A.
86.6
76.4
75.5
73.2
N.A.
N.A.
48.8
43.9
44.6
P-Site Identity:
100
N.A.
20
N.A.
N.A.
100
100
N.A.
33.3
46.6
13.3
13.3
N.A.
N.A.
0
0
0
P-Site Similarity:
100
N.A.
40
N.A.
N.A.
100
100
N.A.
40
53.3
40
46.6
N.A.
N.A.
26.6
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
37
0
0
0
37
19
10
0
0
0
10
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
0
0
0
0
10
0
% D
% Glu:
28
28
10
10
10
10
10
10
0
0
10
10
0
19
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
28
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
10
19
28
55
19
28
0
0
28
10
0
37
37
0
% K
% Leu:
10
0
0
10
10
10
19
0
0
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
28
0
0
0
0
0
0
19
10
10
0
19
0
0
0
% N
% Pro:
0
19
10
37
10
10
0
10
0
10
0
46
19
0
55
% P
% Gln:
10
46
0
0
10
0
0
0
10
19
10
0
0
10
0
% Q
% Arg:
0
0
10
10
10
0
10
0
10
0
64
10
28
10
0
% R
% Ser:
0
0
10
0
0
28
0
37
10
37
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
19
0
0
10
0
0
0
0
10
0
% T
% Val:
19
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _