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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIFC2
All Species:
12.42
Human Site:
T591
Identified Species:
21.03
UniProt:
Q96AC6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AC6
NP_665697.1
838
90147
T591
S
N
R
A
T
A
A
T
A
M
N
Q
R
S
S
Chimpanzee
Pan troglodytes
XP_510997
879
97729
D666
E
F
Q
V
Q
S
V
D
D
I
N
K
V
F
E
Rhesus Macaque
Macaca mulatta
XP_001100393
869
96853
S613
S
E
V
Q
E
K
A
S
D
W
E
Y
T
I
T
Dog
Lupus familis
XP_532358
608
66069
P398
Q
R
P
P
T
G
C
P
G
R
L
L
E
L
K
Cat
Felis silvestris
Mouse
Mus musculus
O08672
792
85667
Q579
P
N
L
E
T
L
H
Q
M
L
S
L
G
R
S
Rat
Rattus norvegicus
Q5XI63
693
76123
E467
H
L
F
S
V
A
Q
E
M
S
G
Q
G
W
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515852
1144
125577
T691
H
X
X
X
X
E
H
T
N
L
N
E
H
S
S
Chicken
Gallus gallus
XP_413996
427
46460
D218
F
S
V
Q
S
V
E
D
I
N
K
V
F
E
F
Frog
Xenopus laevis
P79955
643
71930
F433
A
K
G
W
Q
Y
T
F
T
A
S
F
L
E
I
Zebra Danio
Brachydanio rerio
XP_696785
1050
118323
T840
L
G
H
M
N
R
A
T
A
C
T
N
L
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20480
700
77455
T480
W
E
Y
E
I
K
A
T
F
L
E
I
Y
N
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P45962
598
67305
S389
I
R
D
L
L
N
T
S
N
T
N
L
A
I
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002317602
1129
125823
T665
N
A
R
A
V
G
S
T
N
A
N
E
H
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81635
987
109990
T591
M
N
R
A
V
S
S
T
A
M
N
D
R
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.7
29.4
60.8
N.A.
73.1
27.6
N.A.
25.7
23.7
25.5
31
N.A.
22.7
N.A.
24.4
N.A.
Protein Similarity:
100
45.7
47.1
63.8
N.A.
77.4
40
N.A.
39.8
33.2
40.9
45.1
N.A.
38
N.A.
41.2
N.A.
P-Site Identity:
100
6.6
13.3
6.6
N.A.
20
13.3
N.A.
26.6
0
0
20
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
33.3
26.6
6.6
N.A.
33.3
26.6
N.A.
40
13.3
13.3
26.6
N.A.
26.6
N.A.
13.3
N.A.
Percent
Protein Identity:
20.7
N.A.
N.A.
23.9
N.A.
N.A.
Protein Similarity:
35
N.A.
N.A.
39.3
N.A.
N.A.
P-Site Identity:
40
N.A.
N.A.
66.6
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
22
0
15
29
0
22
15
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
15
15
0
0
8
0
0
0
% D
% Glu:
8
15
0
15
8
8
8
8
0
0
15
15
8
15
22
% E
% Phe:
8
8
8
0
0
0
0
8
8
0
0
8
8
8
8
% F
% Gly:
0
8
8
0
0
15
0
0
8
0
8
0
15
0
0
% G
% His:
15
0
8
0
0
0
15
0
0
0
0
0
15
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
8
8
0
8
0
15
8
% I
% Lys:
0
8
0
0
0
15
0
0
0
0
8
8
0
0
8
% K
% Leu:
8
8
8
8
8
8
0
0
0
22
8
22
15
8
0
% L
% Met:
8
0
0
8
0
0
0
0
15
15
0
0
0
0
0
% M
% Asn:
8
22
0
0
8
8
0
0
22
8
43
8
0
15
0
% N
% Pro:
8
0
8
8
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
15
15
0
8
8
0
0
0
15
0
0
0
% Q
% Arg:
0
15
22
0
0
8
0
0
0
8
0
0
15
8
8
% R
% Ser:
15
8
0
8
8
15
15
15
0
8
15
0
0
29
36
% S
% Thr:
0
0
0
0
22
0
15
43
8
8
8
0
8
0
15
% T
% Val:
0
0
15
8
22
8
8
0
0
0
0
8
8
0
0
% V
% Trp:
8
0
0
8
0
0
0
0
0
8
0
0
0
8
0
% W
% Tyr:
0
0
8
0
0
8
0
0
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _