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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIFC2
All Species:
3.94
Human Site:
S116
Identified Species:
6.67
UniProt:
Q96AC6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96AC6
NP_665697.1
838
90147
S116
G
Q
S
G
E
V
P
S
L
L
T
V
T
S
Q
Chimpanzee
Pan troglodytes
XP_510997
879
97729
K161
Q
V
E
H
L
K
E
K
L
I
S
Q
A
Q
E
Rhesus Macaque
Macaca mulatta
XP_001100393
869
96853
A129
A
R
S
A
A
R
P
A
L
A
Q
C
R
A
L
Dog
Lupus familis
XP_532358
608
66069
D46
R
G
G
R
R
R
P
D
P
P
T
A
E
L
W
Cat
Felis silvestris
Mouse
Mus musculus
O08672
792
85667
P116
G
K
P
G
E
V
P
P
L
L
T
V
T
S
Q
Rat
Rattus norvegicus
Q5XI63
693
76123
R92
V
T
K
V
D
T
S
R
P
R
G
P
P
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515852
1144
125577
K170
Q
V
E
N
L
K
G
K
L
T
G
Q
T
R
E
Chicken
Gallus gallus
XP_413996
427
46460
Frog
Xenopus laevis
P79955
643
71930
M81
G
R
Q
S
L
A
V
M
R
P
K
N
S
G
P
Zebra Danio
Brachydanio rerio
XP_696785
1050
118323
R209
R
S
E
D
A
A
K
R
L
L
L
Q
R
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20480
700
77455
S117
A
A
A
P
S
L
P
S
I
P
S
K
V
S
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P45962
598
67305
E37
R
I
L
E
T
H
I
E
T
K
D
R
L
L
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002317602
1129
125823
S95
T
P
C
V
K
F
S
S
V
F
Q
T
F
N
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81635
987
109990
D105
S
K
V
V
E
A
P
D
D
V
A
D
G
A
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.7
29.4
60.8
N.A.
73.1
27.6
N.A.
25.7
23.7
25.5
31
N.A.
22.7
N.A.
24.4
N.A.
Protein Similarity:
100
45.7
47.1
63.8
N.A.
77.4
40
N.A.
39.8
33.2
40.9
45.1
N.A.
38
N.A.
41.2
N.A.
P-Site Identity:
100
6.6
20
13.3
N.A.
80
0
N.A.
13.3
0
6.6
20
N.A.
20
N.A.
0
N.A.
P-Site Similarity:
100
26.6
40
13.3
N.A.
86.6
6.6
N.A.
20
0
20
20
N.A.
53.3
N.A.
6.6
N.A.
Percent
Protein Identity:
20.7
N.A.
N.A.
23.9
N.A.
N.A.
Protein Similarity:
35
N.A.
N.A.
39.3
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
8
8
15
22
0
8
0
8
8
8
8
15
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
15
8
0
8
8
0
0
0
% D
% Glu:
0
0
22
8
22
0
8
8
0
0
0
0
8
0
15
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% F
% Gly:
22
8
8
15
0
0
8
0
0
0
15
0
8
8
0
% G
% His:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
8
0
8
8
0
0
0
0
0
% I
% Lys:
0
15
8
0
8
15
8
15
0
8
8
8
0
0
8
% K
% Leu:
0
0
8
0
22
8
0
0
43
22
8
0
8
29
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
8
8
8
0
0
43
8
15
22
0
8
8
0
8
% P
% Gln:
15
8
8
0
0
0
0
0
0
0
15
22
0
8
22
% Q
% Arg:
22
15
0
8
8
15
0
15
8
8
0
8
15
8
15
% R
% Ser:
8
8
15
8
8
0
15
22
0
0
15
0
8
22
8
% S
% Thr:
8
8
0
0
8
8
0
0
8
8
22
8
22
0
0
% T
% Val:
8
15
8
22
0
15
8
0
8
8
0
15
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _