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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADC
All Species:
28.18
Human Site:
Y317
Identified Species:
47.69
UniProt:
Q96A70
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96A70
NP_443724.1
460
49980
Y317
S
T
S
K
T
I
V
Y
H
L
D
E
G
V
Y
Chimpanzee
Pan troglodytes
XP_524555
420
45293
E311
L
D
Q
P
G
R
E
E
E
N
G
S
T
S
K
Rhesus Macaque
Macaca mulatta
XP_001106869
460
49820
Y317
S
T
T
K
T
V
V
Y
H
L
D
E
G
V
Y
Dog
Lupus familis
XP_535320
460
49774
Y317
S
T
P
K
T
I
V
Y
H
L
G
E
G
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVM4
459
49484
Y316
A
A
P
K
S
I
V
Y
Y
L
D
E
G
V
Y
Rat
Rattus norvegicus
P09057
461
51029
Y316
S
N
E
Q
T
L
M
Y
Y
V
N
D
G
V
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516497
344
37229
D235
G
Y
R
M
H
L
L
D
L
G
G
G
F
P
G
Chicken
Gallus gallus
P27118
450
49716
Y306
V
N
D
K
T
L
M
Y
Y
V
N
D
G
V
Y
Frog
Xenopus laevis
Q9I8S4
456
50618
Y313
E
S
S
K
S
I
M
Y
Y
V
N
D
G
V
Y
Zebra Danio
Brachydanio rerio
NP_571876
461
50770
Y317
S
N
D
R
T
L
M
Y
Y
V
N
D
G
V
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40807
394
44176
K284
L
V
C
K
I
H
A
K
R
E
I
R
N
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41931
422
46901
H312
D
P
K
D
C
A
D
H
G
Y
M
Y
Y
I
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P08432
466
52267
G355
Y
T
N
D
G
V
Y
G
N
M
N
C
I
L
F
Red Bread Mold
Neurospora crassa
P27121
484
53282
V366
N
G
D
A
R
Y
M
V
Y
V
N
D
G
L
Y
Conservation
Percent
Protein Identity:
100
78.4
97.3
88.2
N.A.
86
49
N.A.
50.6
49.3
60
50.5
N.A.
35
N.A.
31.5
N.A.
Protein Similarity:
100
81.7
98.4
93
N.A.
92.6
70.9
N.A.
61.2
68.9
77.1
70.5
N.A.
52.8
N.A.
54.1
N.A.
P-Site Identity:
100
0
86.6
86.6
N.A.
66.6
40
N.A.
0
40
46.6
40
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
0
100
86.6
N.A.
86.6
86.6
N.A.
13.3
80
93.3
86.6
N.A.
6.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.9
32.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.6
50.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
8
8
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
8
0
8
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
8
22
15
0
0
8
8
0
0
22
36
0
0
0
% D
% Glu:
8
0
8
0
0
0
8
8
8
8
0
29
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% F
% Gly:
8
8
0
0
15
0
0
8
8
8
22
8
65
0
8
% G
% His:
0
0
0
0
8
8
0
8
22
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
29
0
0
0
0
8
0
8
8
0
% I
% Lys:
0
0
8
50
0
0
0
8
0
0
0
0
0
0
8
% K
% Leu:
15
0
0
0
0
29
8
0
8
29
0
0
0
15
0
% L
% Met:
0
0
0
8
0
0
36
0
0
8
8
0
0
0
0
% M
% Asn:
8
22
8
0
0
0
0
0
8
8
43
0
8
0
8
% N
% Pro:
0
8
15
8
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
8
8
8
0
0
8
0
0
8
0
0
0
% R
% Ser:
36
8
15
0
15
0
0
0
0
0
0
8
0
8
0
% S
% Thr:
0
29
8
0
43
0
0
0
0
0
0
0
8
0
0
% T
% Val:
8
8
0
0
0
15
29
8
0
36
0
0
0
58
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
8
8
58
43
8
0
8
8
0
65
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _