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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADC
All Species:
33.33
Human Site:
S177
Identified Species:
56.41
UniProt:
Q96A70
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96A70
NP_443724.1
460
49980
S177
K
F
G
V
S
L
K
S
C
R
H
L
L
E
N
Chimpanzee
Pan troglodytes
XP_524555
420
45293
S182
K
F
G
V
S
L
K
S
C
R
H
L
L
E
N
Rhesus Macaque
Macaca mulatta
XP_001106869
460
49820
S177
K
F
G
V
S
L
K
S
C
R
H
L
L
E
N
Dog
Lupus familis
XP_535320
460
49774
S177
K
F
G
A
S
L
K
S
C
R
H
L
L
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVM4
459
49484
S177
R
F
G
A
S
L
K
S
C
R
H
L
L
E
N
Rat
Rattus norvegicus
P09057
461
51029
T176
K
F
G
A
T
L
K
T
S
R
L
L
L
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516497
344
37229
H108
Q
S
I
G
V
P
G
H
K
I
I
Y
A
N
P
Chicken
Gallus gallus
P27118
450
49716
T166
K
F
G
A
T
L
K
T
S
R
L
L
L
E
R
Frog
Xenopus laevis
Q9I8S4
456
50618
S175
K
F
G
A
P
L
K
S
C
R
R
L
L
E
M
Zebra Danio
Brachydanio rerio
NP_571876
461
50770
S176
K
F
G
A
T
L
K
S
S
R
L
L
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40807
394
44176
Q156
K
S
E
A
K
E
A
Q
C
P
L
G
D
K
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41931
422
46901
I178
K
F
G
A
D
P
I
I
A
A
P
Q
L
L
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P08432
466
52267
N223
K
Y
G
C
E
M
E
N
V
D
V
L
L
K
A
Red Bread Mold
Neurospora crassa
P27121
484
53282
S221
K
F
G
A
S
L
D
S
T
D
G
L
L
G
L
Conservation
Percent
Protein Identity:
100
78.4
97.3
88.2
N.A.
86
49
N.A.
50.6
49.3
60
50.5
N.A.
35
N.A.
31.5
N.A.
Protein Similarity:
100
81.7
98.4
93
N.A.
92.6
70.9
N.A.
61.2
68.9
77.1
70.5
N.A.
52.8
N.A.
54.1
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
60
N.A.
0
60
73.3
66.6
N.A.
13.3
N.A.
26.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
73.3
N.A.
6.6
73.3
73.3
73.3
N.A.
20
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.9
32.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.6
50.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
65
0
0
8
0
8
8
0
0
8
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
50
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
0
0
15
0
0
8
0
0
% D
% Glu:
0
0
8
0
8
8
8
0
0
0
0
0
0
65
0
% E
% Phe:
0
79
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
86
8
0
0
8
0
0
0
8
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
36
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
8
0
8
8
0
0
0
0
% I
% Lys:
86
0
0
0
8
0
65
0
8
0
0
0
0
15
8
% K
% Leu:
0
0
0
0
0
72
0
0
0
0
29
79
86
8
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
36
% N
% Pro:
0
0
0
0
8
15
0
0
0
8
8
0
0
0
8
% P
% Gln:
8
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
65
8
0
0
0
22
% R
% Ser:
0
15
0
0
43
0
0
58
22
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
22
0
0
15
8
0
0
0
0
0
0
% T
% Val:
0
0
0
22
8
0
0
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _